Abstract
The molecular identity of the signal coupling intracellular Ca2+ store depletion to the activation of Ca2+ entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca2+ content is sensed and communicated to store-operated Ca2+ channels at the cell surface.
| Original language | English (US) |
|---|---|
| Pages (from-to) | R493-R495 |
| Journal | Current Biology |
| Volume | 15 |
| Issue number | 13 |
| DOIs | |
| State | Published - Jul 12 2005 |
| Externally published | Yes |