TY - JOUR
T1 - Cellular RNA helicases and HIV-1
T2 - insights from genome-wide, proteomic, and molecular studies.
AU - Chen, Chia Yen
AU - Liu, Xiang
AU - Boris-Lawrie, Kathleen
AU - Sharma, Amit
AU - Jeang, Kuan Teh
PY - 2013/2
Y1 - 2013/2
N2 - RNA helicases are ubiquitous in plants and animals and function in many cellular processes. Retroviruses, such as human immunodeficiency virus (HIV-1), encode no RNA helicases in their genomes and utilize host cellular RNA helicases at various stages of their life cycle. Here, we briefly summarize the roles RNA helicases play in HIV-1 replication that have been identified recently, in part, through genome-wide screenings, proteomics, and molecular studies. Some of these helicases augment virus propagation while others apparently participate in antiviral defenses against viral replication. Published by Elsevier B.V.
AB - RNA helicases are ubiquitous in plants and animals and function in many cellular processes. Retroviruses, such as human immunodeficiency virus (HIV-1), encode no RNA helicases in their genomes and utilize host cellular RNA helicases at various stages of their life cycle. Here, we briefly summarize the roles RNA helicases play in HIV-1 replication that have been identified recently, in part, through genome-wide screenings, proteomics, and molecular studies. Some of these helicases augment virus propagation while others apparently participate in antiviral defenses against viral replication. Published by Elsevier B.V.
UR - http://www.scopus.com/inward/record.url?scp=85027936961&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85027936961&partnerID=8YFLogxK
U2 - 10.1016/j.virusres.2012.06.022
DO - 10.1016/j.virusres.2012.06.022
M3 - Review article
C2 - 22814432
AN - SCOPUS:85027936961
SN - 0022-1120
VL - 171
SP - 357
EP - 365
JO - Unknown Journal
JF - Unknown Journal
IS - 2
ER -
