Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012

Michael A. Matthay; Piero Anversa; Jahar Bhattacharya; Bruce K. Burnett; Harold A. Chapman; Joshua M. Hare; Derek J. Hei; Andrew M. Hoffman; Stella Kourembanas; David H. McKenna; Luis A. Ortiz; Harald C. Ott; William Tente; Bernard Thebaud; Bruce C. Trapnell; Daniel J. Weiss; Jason X.J. Yuan; Carol J. Blaisdell

doi:10.1164/rccm.201303-0522WS

Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012

Michael A. Matthay, Piero Anversa, Jahar Bhattacharya, Bruce K. Burnett, Harold A. Chapman, Joshua M. Hare, Derek J. Hei, Andrew M. Hoffman, Stella Kourembanas, David H. McKenna, Luis A. Ortiz, Harald C. Ott, William Tente, Bernard Thebaud, Bruce C. Trapnell, Daniel J. Weiss, Jason X.J. Yuan, Carol J. Blaisdell

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27 Scopus citations

Abstract

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened the Cell Therapy for Lung Disease Working Group on November 13-14, 2012, to review and formulate recommendations for future research directions. The workshop brought together investigators studying basic mechanisms and the roles of cell therapy in preclinical models of lung injury and pulmonary vascular disease, with clinical trial experts in cell therapy for cardiovascular diseases and experts from the NHLBI Production Assistance for Cell Therapy program. The purpose of the workshop was to discuss the current status of basic investigations in lung cell therapy, to identify some of the scientific gaps in current knowledge regarding the potential roles and mechanismsof cell therapy in the treatment of lung diseases, and to develop recommendations to the NHLBI and the research community on scientific priorities and practical steps that would lead to first-in-human trials of lung cell therapy.

Original language	English (US)
Pages (from-to)	370-375
Number of pages	6
Journal	American journal of respiratory and critical care medicine
Volume	188
Issue number	3
DOIs	https://doi.org/10.1164/rccm.201303-0522WS
State	Published - Aug 1 2013

Keywords

Epithelial and endothelial progenitor cells
Lung stem cells
Mesenchymal stromal (stem) cells

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1164/rccm.201303-0522WS

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Matthay, M. A., Anversa, P., Bhattacharya, J., Burnett, B. K., Chapman, H. A., Hare, J. M., Hei, D. J., Hoffman, A. M., Kourembanas, S., McKenna, D. H., Ortiz, L. A., Ott, H. C., Tente, W., Thebaud, B., Trapnell, B. C., Weiss, D. J., Yuan, J. X. J., & Blaisdell, C. J. (2013). Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012. American journal of respiratory and critical care medicine, 188(3), 370-375. https://doi.org/10.1164/rccm.201303-0522WS

Matthay, MA, Anversa, P, Bhattacharya, J, Burnett, BK, Chapman, HA, Hare, JM, Hei, DJ, Hoffman, AM, Kourembanas, S, McKenna, DH, Ortiz, LA, Ott, HC, Tente, W, Thebaud, B, Trapnell, BC, Weiss, DJ, Yuan, JXJ & Blaisdell, CJ 2013, 'Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012', American journal of respiratory and critical care medicine, vol. 188, no. 3, pp. 370-375. https://doi.org/10.1164/rccm.201303-0522WS

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abstract = "The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened the Cell Therapy for Lung Disease Working Group on November 13-14, 2012, to review and formulate recommendations for future research directions. The workshop brought together investigators studying basic mechanisms and the roles of cell therapy in preclinical models of lung injury and pulmonary vascular disease, with clinical trial experts in cell therapy for cardiovascular diseases and experts from the NHLBI Production Assistance for Cell Therapy program. The purpose of the workshop was to discuss the current status of basic investigations in lung cell therapy, to identify some of the scientific gaps in current knowledge regarding the potential roles and mechanismsof cell therapy in the treatment of lung diseases, and to develop recommendations to the NHLBI and the research community on scientific priorities and practical steps that would lead to first-in-human trials of lung cell therapy.",

keywords = "Epithelial and endothelial progenitor cells, Lung stem cells, Mesenchymal stromal (stem) cells",

author = "Matthay, {Michael A.} and Piero Anversa and Jahar Bhattacharya and Burnett, {Bruce K.} and Chapman, {Harold A.} and Hare, {Joshua M.} and Hei, {Derek J.} and Hoffman, {Andrew M.} and Stella Kourembanas and McKenna, {David H.} and Ortiz, {Luis A.} and Ott, {Harald C.} and William Tente and Bernard Thebaud and Trapnell, {Bruce C.} and Weiss, {Daniel J.} and Yuan, {Jason X.J.} and Blaisdell, {Carol J.}",

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AU - Hei, Derek J.

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AU - Kourembanas, Stella

AU - McKenna, David H.

AU - Ortiz, Luis A.

AU - Ott, Harald C.

AU - Tente, William

AU - Thebaud, Bernard

AU - Trapnell, Bruce C.

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AU - Yuan, Jason X.J.

AU - Blaisdell, Carol J.

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N2 - The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened the Cell Therapy for Lung Disease Working Group on November 13-14, 2012, to review and formulate recommendations for future research directions. The workshop brought together investigators studying basic mechanisms and the roles of cell therapy in preclinical models of lung injury and pulmonary vascular disease, with clinical trial experts in cell therapy for cardiovascular diseases and experts from the NHLBI Production Assistance for Cell Therapy program. The purpose of the workshop was to discuss the current status of basic investigations in lung cell therapy, to identify some of the scientific gaps in current knowledge regarding the potential roles and mechanismsof cell therapy in the treatment of lung diseases, and to develop recommendations to the NHLBI and the research community on scientific priorities and practical steps that would lead to first-in-human trials of lung cell therapy.

AB - The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened the Cell Therapy for Lung Disease Working Group on November 13-14, 2012, to review and formulate recommendations for future research directions. The workshop brought together investigators studying basic mechanisms and the roles of cell therapy in preclinical models of lung injury and pulmonary vascular disease, with clinical trial experts in cell therapy for cardiovascular diseases and experts from the NHLBI Production Assistance for Cell Therapy program. The purpose of the workshop was to discuss the current status of basic investigations in lung cell therapy, to identify some of the scientific gaps in current knowledge regarding the potential roles and mechanismsof cell therapy in the treatment of lung diseases, and to develop recommendations to the NHLBI and the research community on scientific priorities and practical steps that would lead to first-in-human trials of lung cell therapy.

KW - Epithelial and endothelial progenitor cells

KW - Lung stem cells

KW - Mesenchymal stromal (stem) cells

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Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012

Abstract

Keywords

UN SDGs

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