Cell-sized mechanosensitive and biosensing compartment programmed with DNA

Sagardip Majumder, Jonathan Garamella, Ying Lin Wang, Maxwell Denies, Vincent Noireaux, Allen P. Liu

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

The bottom-up construction of cell-sized compartments programmed with DNA that are capable of sensing the chemical and physical environment remains challenging in synthetic cell engineering. Here, we construct mechanosensitive liposomes with biosensing capability by expressing the E. coli channel MscL and a calcium biosensor using cell-free expression.

Original languageEnglish (US)
Pages (from-to)7349-7352
Number of pages4
JournalChemical Communications
Volume53
Issue number53
DOIs
StatePublished - 2017

Bibliographical note

Publisher Copyright:
© 2017 The Royal Society of Chemistry.

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