Cell biology of sarcomeric protein engineering: Disease modeling and therapeutic potential

Keyphrases

• Cell Biology 100%
• Protein Engineering 100%
• Therapeutic Potential 100%
• Disease Modeling 100%
• Sarcomeric Proteins 100%
• Diseases Therapeutic 100%
• Gene Therapy 50%
• Ischemia 50%
• Hypertrophic Cardiomyopathy 50%
• Disease States 50%
• Contractility 50%
• Restrictive Cardiomyopathy 50%
• Molecular Mechanism 25%
• Genetic Engineering 25%
• Structure Function 25%
• Sarcomere Function 25%
• Pathophysiologic 25%
• Cardiac Troponin 25%
• Ordered Arrays 25%
• Mutant Protein 25%
• Histidine 25%
• Insults 25%
• Disease-causing mutations 25%
• Cellular Context 25%
• Adult Cardiac Myocytes 25%
• Potential Genes 25%
• Inherited mutation 25%
• Acidosis 25%
• Sarcomeric Genes 25%
• Cardiac Sarcomere 25%
• Myocyte Contraction 25%
• Acquired Heart Disease 25%
• CTnI 25%
• Inherited Cardiac Conditions 25%
• Stoichiometric Balance 25%

Medicine and Dentistry

• Cytotechnology 100%
• Disease 100%
• Protein Engineering 100%
• Gene Therapy 40%
• Ischemia 40%
• Muscle Contractility 40%
• Hypertrophic Cardiomyopathy 40%
• Sarcomere 40%
• Restrictive Cardiomyopathy 40%
• Isotopes of Calcium 20%
• Heart Disease 20%
• Cardiac Troponin 20%
• Troponin I 20%
• Genetic Engineering 20%
• Acidosis 20%
• Muscle Cell 20%
• Cardiac Muscle Cell 20%
• Mutant Protein 20%
• Histidine 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Disease 100%
• Ischemia 40%
• Hypertrophic Cardiomyopathy 40%
• Restrictive Cardiomyopathy 40%
• Heart Disease 20%
• Mutant Protein 20%
• Troponin I 20%
• Histidine 20%