Historically, most immune response studies have been limited to analyses of lymphoid tissue. However, peripheral sites of infection are likely to represent important sites of cell-mediated immune surveillance and effector function. Recent debates have centered on the persistence, trafficking patterns, effector activity, and protective role of non-lymphoid memory T cells.
Bibliographical noteFunding Information:
This work was supported by USPHS grants DK45260 and AI41576. DM was supported by USPHS Training Grant T32-AI07080.
- T cell