Case Report: Histoplasma Hepatitis Presenting as Common Bile Duct Obstruction

Brittany Hjermstad, Dale Snover, Jose D. Debes

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Histoplasma capsulatum is the most common endemic mycosis in the United States and can cause disseminated histoplasmosis in immunocompromised patients.1 Although hepatic involvement is common with histoplasmosis, it can be challenging to diagnose. We report a case of a 50-year-old woman receiving adalimumab for rheumatoid arthritis who presented with right upper quadrant pain, fever, jaundice, and dyspnea. The initial working diagnosis was biliary obstruction with potential COVID-19 infection. Endoscopic retrograde cholangiopancreatography suggested Mirizzi syndrome, but successful sphincterotomy failed to improve jaundice over subsequent days. Bronchoscopy and liver biopsy were performed, with the first revealing budding yeast and the later growing H. capsulatum. The patient improved with the initiation of itraconazole therapy.

Original languageEnglish (US)
Pages (from-to)1627-1628
Number of pages2
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number6
StatePublished - Jun 2022

Bibliographical note

Publisher Copyright:
Copyright © 2022 by The American Society of Tropical Medicine and Hygiene.


Dive into the research topics of 'Case Report: Histoplasma Hepatitis Presenting as Common Bile Duct Obstruction'. Together they form a unique fingerprint.

Cite this