Case Report: Hematologic Recovery Following Stereotactic Ablative Radiotherapy in a Patient With Early-Stage Non-Small Cell Lung Cancer and Paraneoplastic Myelofibrosis

Lindsey Sloan; Rakhi P. Naik; Kavita Umrau; Rena Ruiyu Xian; Kristen A. Marrone; Khinh Ranh Voong

doi:10.3389/fonc.2022.842620

Case Report: Hematologic Recovery Following Stereotactic Ablative Radiotherapy in a Patient With Early-Stage Non-Small Cell Lung Cancer and Paraneoplastic Myelofibrosis

Lindsey Sloan, Rakhi P. Naik, Kavita Umrau, Rena Ruiyu Xian, Kristen A. Marrone, Khinh Ranh Voong

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Herein, we report the first case presentation of paraneoplastic myelofibrosis associated with cancer. Paraneoplastic syndromes occur in some patients with thoracic malignancies; however, myelofibrosis is not commonly seen in non-small cell lung cancer (NSCLC). We report a case of myelofibrosis in a patient with a new diagnosis of NSCLC that resolved after stereotactic ablative radiotherapy (SABR). In conclusion, NSCLC may evoke unexpected systemic effects that resolve with treatment.

Original language	English (US)
Article number	842620
Journal	Frontiers in Oncology
Volume	12
DOIs	https://doi.org/10.3389/fonc.2022.842620
State	Published - Feb 24 2022

Bibliographical note

Publisher Copyright:
Copyright © 2022 Sloan, Naik, Umrau, Xian, Marrone and Voong.

Keywords

NSCLC
SAbR
case
paraneoplastic
report

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3389/fonc.2022.842620

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abstract = "Herein, we report the first case presentation of paraneoplastic myelofibrosis associated with cancer. Paraneoplastic syndromes occur in some patients with thoracic malignancies; however, myelofibrosis is not commonly seen in non-small cell lung cancer (NSCLC). We report a case of myelofibrosis in a patient with a new diagnosis of NSCLC that resolved after stereotactic ablative radiotherapy (SABR). In conclusion, NSCLC may evoke unexpected systemic effects that resolve with treatment.",

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AU - Xian, Rena Ruiyu

AU - Marrone, Kristen A.

AU - Voong, Khinh Ranh

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AB - Herein, we report the first case presentation of paraneoplastic myelofibrosis associated with cancer. Paraneoplastic syndromes occur in some patients with thoracic malignancies; however, myelofibrosis is not commonly seen in non-small cell lung cancer (NSCLC). We report a case of myelofibrosis in a patient with a new diagnosis of NSCLC that resolved after stereotactic ablative radiotherapy (SABR). In conclusion, NSCLC may evoke unexpected systemic effects that resolve with treatment.

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Case Report: Hematologic Recovery Following Stereotactic Ablative Radiotherapy in a Patient With Early-Stage Non-Small Cell Lung Cancer and Paraneoplastic Myelofibrosis

Abstract

Bibliographical note

Keywords

UN SDGs

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