Case report: FGF4L1 retrogene insertion is lacking in the tall dachshund phenotype

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Two retrogene insertions, FGF4L1 (formerly 18-FGF4, colloquially CDPA) and FGF4L2 (formerly 12-FGF4, colloquially CDDY), have recently been discovered as determinants of short leg phenotype in dogs. This case study is comprised of a family of standard wirehaired dachshunds in which the dogs lacking the FGF4L1 gene exhibit a tall phenotype. The tall phenotype in the dachshunds of this report precludes the dog’s working function of den work. The data presented in this report provide information as to how FGF4L1 status could be used in making breeding decisions in dachshunds to maintain working ability without compromising animal health.

Original languageEnglish (US)
Article number1522745
JournalFrontiers in Veterinary Science
Volume11
DOIs
StatePublished - 2024
Externally publishedYes

Bibliographical note

Publisher Copyright:
Copyright © 2025 Sullivan, Szeremeta and Kutzler.

Keywords

  • CDDY
  • CDPA
  • FGF4L1
  • FGF4L2
  • case report
  • chondrodysplasia
  • chondrodystrophy
  • limb-length

PubMed: MeSH publication types

  • Case Reports
  • Journal Article

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