Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential

Callie Blackford Winders, Cynthia M. Bell, Stephanie Goldschmidt

Research output: Contribution to journalArticlepeer-review

Abstract

A 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the right maxilla with a cytoreductive surgery followed by a definitive radiation protocol. Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recurrence of the original maxillary tumor. Both the mandibular mass and the lung nodule were histologically confirmed to be amyloid-producing odontogenic tumor based on the appearance of sheets and cords of the odontogenic epithelium disrupted by amorphous extracellular amyloid. This case illustrates the metastatic potential for amyloid-producing odontogenic tumor in dogs and asynchronous occurrence of multiple APOTs in the oral cavity.

Original languageEnglish (US)
Article number576376
JournalFrontiers in Veterinary Science
Volume7
DOIs
StatePublished - Sep 29 2020

Keywords

  • amyloid producing odontogenic tumor
  • dogs
  • neoplasia
  • odontogenic tumor
  • pathology—head and neck neoplasms

PubMed: MeSH publication types

  • Case Reports

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