Case-Based Learning in Translational Biomedical Research Education: Providing Realistic and Adaptive Skills for Early-Career Scientists

Alexandra J. Greenberg-Worisek, Katherine A. Campbell, Eric W. Klee, Nathan P. Staff, Lisa A. Schimmenti, Karen M. Weavers, Stephen C. Ekker, Anthony J. Windebank

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Problem Case-based learning is an established means of educating students in law, business, and medicine; however, this methodology is not often applied to educating translational biomedical researchers. The application of case-based learning to translational biomedical research education allows scholars to actively engage with real-world material and apply their newfound knowledge as it is acquired. Approach Through the Mayo Clinic Center for Clinical and Translational Science (CCaTS), three courses were delivered in 2009-2017 which emphasized case-based learning in clinical and translational science, entrepreneurship, and individualized medicine. Quantitative measures collected in student course reviews upon course completion were analyzed. Additionally, products arising from each course were identified, including publications and startups pitched. Outcomes Analyses demonstrate that case-based learning techniques are well suited to graduate biomedical research education. Furthermore, case studies can be employed throughout the entire clinical and translational spectrum, from basic and preclinical work through to clinical and population-based learning. Next Steps Within CCaTS, next steps include creating case-based courses in regulatory and team science to continue to allow scholars to learn and apply these critical skills to real-world material. The goal is to continue to provide immersive training opportunities in areas of clinical and translational science that cannot be readily learned in a traditional lecture-based class setting.

Original languageEnglish (US)
Pages (from-to)213-216
Number of pages4
JournalAcademic Medicine
Issue number2
StatePublished - Feb 1 2019

Bibliographical note

Funding Information:
Funding/Support: This project was supported by Clinical and Translational Science Award grant number UL1 TR000135 from the National Center for Advancing Translational Science (NCATS). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health.

Funding Information:
National Institutes of Health

Publisher Copyright:
© 2018 by the Association of AmericanMedical Colleges.

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural


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