Carotid Intima-Media Thickness Testing by Non-Sonographer Clinicians: The Office Practice Assessment of Carotid Atherosclerosis Study

Claudia E. Korcarz; Alan T. Hirsch; Charles Bruce; Jeanne M. DeCara; Emile R. Mohler; Bryan Pogue; John Postley; Wendy S. Tzou; James H. Stein

doi:10.1016/j.echo.2007.08.038

Carotid Intima-Media Thickness Testing by Non-Sonographer Clinicians: The Office Practice Assessment of Carotid Atherosclerosis Study

Claudia E. Korcarz, Alan T. Hirsch, Charles Bruce, Jeanne M. DeCara, Emile R. Mohler, Bryan Pogue, John Postley, Wendy S. Tzou, James H. Stein

Medicine - Cardiology Division

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Background: The purpose of this study was to determine whether a non-sonographer clinician (NSC) could obtain ultrasound images of the carotid artery, measure carotid intima-media thickness (CIMT), and identify findings indicating increased cardiovascular risk in an office setting. Methods: Eight NSCs from five sites were trained to use a handheld ultrasound device to screen the carotid arteries for plaques and to measure CIMT. Results: NSCs scanned 150 subjects who provided 900 images, of which 873 (97%) were interpretable. Differences between NSCs and the core laboratory were small (0.002 ± 0.004 mm) and bioequivalent (P_TOST < 0.05) with a low coefficient of variation (3.9% ± 0.5%). There was ≥ 90% agreement on the presence of CIMT ≥ 75th percentile and ≥ 80% agreement on plaque presence. Conclusions: This is the first multicenter study to show that NSCs can obtain images of the carotid arteries using a handheld ultrasound device, accurately measure CIMT, and identify findings indicating increased cardiovascular risk.

Original language	English (US)
Pages (from-to)	117-122
Number of pages	6
Journal	Journal of the American Society of Echocardiography
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/j.echo.2007.08.038
State	Published - Feb 2008

Bibliographical note

Funding Information:
This study was funded by Sonosite, Inc. Sonosite, Inc. also provided ultrasound equipment and the semiautomated border detection software used in this study, as well as technical support for its use. Sonosite, Inc. had no role in the design or analysis of the data from of the study and did not contribute to the content of this article.

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

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10.1016/j.echo.2007.08.038

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Korcarz, C. E., Hirsch, A. T., Bruce, C., DeCara, J. M., Mohler, E. R., Pogue, B., Postley, J., Tzou, W. S., & Stein, J. H. (2008). Carotid Intima-Media Thickness Testing by Non-Sonographer Clinicians: The Office Practice Assessment of Carotid Atherosclerosis Study. Journal of the American Society of Echocardiography, 21(2), 117-122. https://doi.org/10.1016/j.echo.2007.08.038

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abstract = "Background: The purpose of this study was to determine whether a non-sonographer clinician (NSC) could obtain ultrasound images of the carotid artery, measure carotid intima-media thickness (CIMT), and identify findings indicating increased cardiovascular risk in an office setting. Methods: Eight NSCs from five sites were trained to use a handheld ultrasound device to screen the carotid arteries for plaques and to measure CIMT. Results: NSCs scanned 150 subjects who provided 900 images, of which 873 (97%) were interpretable. Differences between NSCs and the core laboratory were small (0.002 ± 0.004 mm) and bioequivalent (PTOST < 0.05) with a low coefficient of variation (3.9% ± 0.5%). There was ≥ 90% agreement on the presence of CIMT ≥ 75th percentile and ≥ 80% agreement on plaque presence. Conclusions: This is the first multicenter study to show that NSCs can obtain images of the carotid arteries using a handheld ultrasound device, accurately measure CIMT, and identify findings indicating increased cardiovascular risk.",

author = "Korcarz, {Claudia E.} and Hirsch, {Alan T.} and Charles Bruce and DeCara, {Jeanne M.} and Mohler, {Emile R.} and Bryan Pogue and John Postley and Tzou, {Wendy S.} and Stein, {James H.}",

note = "Funding Information: This study was funded by Sonosite, Inc. Sonosite, Inc. also provided ultrasound equipment and the semiautomated border detection software used in this study, as well as technical support for its use. Sonosite, Inc. had no role in the design or analysis of the data from of the study and did not contribute to the content of this article. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

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doi = "10.1016/j.echo.2007.08.038",

language = "English (US)",

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pages = "117--122",

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AU - Mohler, Emile R.

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AU - Postley, John

AU - Tzou, Wendy S.

AU - Stein, James H.

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N2 - Background: The purpose of this study was to determine whether a non-sonographer clinician (NSC) could obtain ultrasound images of the carotid artery, measure carotid intima-media thickness (CIMT), and identify findings indicating increased cardiovascular risk in an office setting. Methods: Eight NSCs from five sites were trained to use a handheld ultrasound device to screen the carotid arteries for plaques and to measure CIMT. Results: NSCs scanned 150 subjects who provided 900 images, of which 873 (97%) were interpretable. Differences between NSCs and the core laboratory were small (0.002 ± 0.004 mm) and bioequivalent (PTOST < 0.05) with a low coefficient of variation (3.9% ± 0.5%). There was ≥ 90% agreement on the presence of CIMT ≥ 75th percentile and ≥ 80% agreement on plaque presence. Conclusions: This is the first multicenter study to show that NSCs can obtain images of the carotid arteries using a handheld ultrasound device, accurately measure CIMT, and identify findings indicating increased cardiovascular risk.

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Carotid Intima-Media Thickness Testing by Non-Sonographer Clinicians: The Office Practice Assessment of Carotid Atherosclerosis Study

Abstract

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