Care After Chemotherapy: Peripheral Neuropathy, Cannabis for Symptom Control, and Mindfulness

Deanna Teoh, Thomas J Smith, Mihae Song, Nick M Spirtos

Research output: Contribution to journalReview articlepeer-review


As cancer therapies improve, patients are living longer. With these improvements in therapy comes a responsibility to optimize patients' quality of life during cancer therapy and beyond. This report reviews three timely and important topics. The first section reviews the mechanism underlying chemotherapy-induced peripheral neuropathy and evaluates the evidence for interventions to prevent and treat peripheral neuropathy. It also provides a framework for approaching the diagnosis and management of this common and bothersome side effect. The second section addresses the controversial but effective use of cannabinoids for cancer and chemotherapy symptoms. Although clinical trials are difficult to conduct because of the political and social stigma of this class of drugs, this review provides evidence of the efficacy of cannabinoids for treatment of pain and nausea. The last section addresses the mind-body connection, with a focus on the negative emotions patients with cancer often experience. This section assesses the literature regarding mindfulness-based programs to improve cancer-related stress. These three topics may appear unrelated, but all address one common goal: treating the body and the mind to optimize quality of life during and after cancer therapy.

Original languageEnglish (US)
Pages (from-to)469-479
Number of pages11
JournalAmerican Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
StatePublished - May 23 2018
Externally publishedYes


  • Antineoplastic Combined Chemotherapy Protocols/adverse effects
  • Humans
  • Medical Marijuana/therapeutic use
  • Mindfulness/methods
  • Neoplasms/complications
  • Peripheral Nervous System Diseases/diagnosis
  • Research
  • Treatment Outcome

PubMed: MeSH publication types

  • Journal Article
  • Review

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