Cardiorespiratory interactions and blood flow generation during cardiac arrest and other states of low blood flow

Gardar Sigurdsson, Demetri Yannopoulos, Scott H. McKnite, Keith G Lurie

Research output: Contribution to journalReview article

22 Citations (Scopus)

Abstract

Purpose of review: Recent advances in cardiopulmonary resuscitation have shed light on the importance of cardiorespiratory interactions during shock and cardiac arrest. This review focuses on recently published studies that evaluate factors that determine preload during chest compression, methods that can augment preload, and the detrimental effects of hyperventilation and interrupting chest compressions. Recent findings: Refilling of the ventricles, so-called ventricular preload, is diminished during cardiovascular collapse and resuscitation from cardiac arrest. In light of the potential detrimental effects and challenges of large-volume fluid resuscitations, other methods have increasing importance. During cardiac arrest, active decompression of the chest and impedance of inspiratory airflow during the recoil of the chest work by increasing negative intrathoracic pressure and, hence, increase refilling of the ventricles and increase cardiac preload, with improvement in survival. Conversely, increased frequency of ventilation has detrimental effects on coronary perfusion pressure and survival rates in cardiac arrest and severe shock. Prolonged interruption of chest compressions for delivering single-rescuer ventilation or analyzing rhythm before shock delivery is associated with decreased survival rate. Summary: Cardiorespiratory interactions are of profound importance in states of cardiovascular collapse in which increased negative intrathoracic pressure during decompression of the chest has a favorable effect and increased intrathoracic pressure with ventilation has a detrimental effect on survival rate.

Original languageEnglish (US)
Pages (from-to)183-188
Number of pages6
JournalCurrent Opinion in Critical Care
Volume9
Issue number3
DOIs
StatePublished - Jun 1 2003

Fingerprint

Heart Arrest
Thorax
Ventilation
Pressure
Shock
Decompression
Resuscitation
Hyperventilation
Cardiopulmonary Resuscitation
Electric Impedance
Heart Ventricles
Perfusion

Keywords

  • Cardiopulmonary interactions
  • Cardiopulmonary resuscitation
  • Shock
  • Survival
  • Ventilatory rate

Cite this

Cardiorespiratory interactions and blood flow generation during cardiac arrest and other states of low blood flow. / Sigurdsson, Gardar; Yannopoulos, Demetri; McKnite, Scott H.; Lurie, Keith G.

In: Current Opinion in Critical Care, Vol. 9, No. 3, 01.06.2003, p. 183-188.

Research output: Contribution to journalReview article

@article{af5936916f5049a8aa8f78eb8146f33f,
title = "Cardiorespiratory interactions and blood flow generation during cardiac arrest and other states of low blood flow",
abstract = "Purpose of review: Recent advances in cardiopulmonary resuscitation have shed light on the importance of cardiorespiratory interactions during shock and cardiac arrest. This review focuses on recently published studies that evaluate factors that determine preload during chest compression, methods that can augment preload, and the detrimental effects of hyperventilation and interrupting chest compressions. Recent findings: Refilling of the ventricles, so-called ventricular preload, is diminished during cardiovascular collapse and resuscitation from cardiac arrest. In light of the potential detrimental effects and challenges of large-volume fluid resuscitations, other methods have increasing importance. During cardiac arrest, active decompression of the chest and impedance of inspiratory airflow during the recoil of the chest work by increasing negative intrathoracic pressure and, hence, increase refilling of the ventricles and increase cardiac preload, with improvement in survival. Conversely, increased frequency of ventilation has detrimental effects on coronary perfusion pressure and survival rates in cardiac arrest and severe shock. Prolonged interruption of chest compressions for delivering single-rescuer ventilation or analyzing rhythm before shock delivery is associated with decreased survival rate. Summary: Cardiorespiratory interactions are of profound importance in states of cardiovascular collapse in which increased negative intrathoracic pressure during decompression of the chest has a favorable effect and increased intrathoracic pressure with ventilation has a detrimental effect on survival rate.",
keywords = "Cardiopulmonary interactions, Cardiopulmonary resuscitation, Shock, Survival, Ventilatory rate",
author = "Gardar Sigurdsson and Demetri Yannopoulos and McKnite, {Scott H.} and Lurie, {Keith G}",
year = "2003",
month = "6",
day = "1",
doi = "10.1097/00075198-200306000-00002",
language = "English (US)",
volume = "9",
pages = "183--188",
journal = "Current Opinion in Critical Care",
issn = "1070-5295",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Cardiorespiratory interactions and blood flow generation during cardiac arrest and other states of low blood flow

AU - Sigurdsson, Gardar

AU - Yannopoulos, Demetri

AU - McKnite, Scott H.

AU - Lurie, Keith G

PY - 2003/6/1

Y1 - 2003/6/1

N2 - Purpose of review: Recent advances in cardiopulmonary resuscitation have shed light on the importance of cardiorespiratory interactions during shock and cardiac arrest. This review focuses on recently published studies that evaluate factors that determine preload during chest compression, methods that can augment preload, and the detrimental effects of hyperventilation and interrupting chest compressions. Recent findings: Refilling of the ventricles, so-called ventricular preload, is diminished during cardiovascular collapse and resuscitation from cardiac arrest. In light of the potential detrimental effects and challenges of large-volume fluid resuscitations, other methods have increasing importance. During cardiac arrest, active decompression of the chest and impedance of inspiratory airflow during the recoil of the chest work by increasing negative intrathoracic pressure and, hence, increase refilling of the ventricles and increase cardiac preload, with improvement in survival. Conversely, increased frequency of ventilation has detrimental effects on coronary perfusion pressure and survival rates in cardiac arrest and severe shock. Prolonged interruption of chest compressions for delivering single-rescuer ventilation or analyzing rhythm before shock delivery is associated with decreased survival rate. Summary: Cardiorespiratory interactions are of profound importance in states of cardiovascular collapse in which increased negative intrathoracic pressure during decompression of the chest has a favorable effect and increased intrathoracic pressure with ventilation has a detrimental effect on survival rate.

AB - Purpose of review: Recent advances in cardiopulmonary resuscitation have shed light on the importance of cardiorespiratory interactions during shock and cardiac arrest. This review focuses on recently published studies that evaluate factors that determine preload during chest compression, methods that can augment preload, and the detrimental effects of hyperventilation and interrupting chest compressions. Recent findings: Refilling of the ventricles, so-called ventricular preload, is diminished during cardiovascular collapse and resuscitation from cardiac arrest. In light of the potential detrimental effects and challenges of large-volume fluid resuscitations, other methods have increasing importance. During cardiac arrest, active decompression of the chest and impedance of inspiratory airflow during the recoil of the chest work by increasing negative intrathoracic pressure and, hence, increase refilling of the ventricles and increase cardiac preload, with improvement in survival. Conversely, increased frequency of ventilation has detrimental effects on coronary perfusion pressure and survival rates in cardiac arrest and severe shock. Prolonged interruption of chest compressions for delivering single-rescuer ventilation or analyzing rhythm before shock delivery is associated with decreased survival rate. Summary: Cardiorespiratory interactions are of profound importance in states of cardiovascular collapse in which increased negative intrathoracic pressure during decompression of the chest has a favorable effect and increased intrathoracic pressure with ventilation has a detrimental effect on survival rate.

KW - Cardiopulmonary interactions

KW - Cardiopulmonary resuscitation

KW - Shock

KW - Survival

KW - Ventilatory rate

UR - http://www.scopus.com/inward/record.url?scp=0038542823&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038542823&partnerID=8YFLogxK

U2 - 10.1097/00075198-200306000-00002

DO - 10.1097/00075198-200306000-00002

M3 - Review article

VL - 9

SP - 183

EP - 188

JO - Current Opinion in Critical Care

JF - Current Opinion in Critical Care

SN - 1070-5295

IS - 3

ER -