TY - JOUR
T1 - Cardiorespiratory Function after Operation for Pectus Excavatum
AU - Johnson, Jonathan N.
AU - Hartman, Tyler K.
AU - Pianosi, Paolo
AU - Driscoll, David J.
PY - 2008/9/1
Y1 - 2008/9/1
N2 - Objective: We performed a review of current data to determine the effect that operation has on pulmonary function, aerobic capacity, and stroke volume in patients with pectus excavatum. Study design: Two reviewers independently assessed clinical trials and collected data on interventions and outcomes. To qualify for inclusion, a study had to include preoperative and postoperative assessment, provide outcomes in either a published percentile or qualified matched control form to control for interval growth, and include only original patient groups. Results: Postoperative total lung capacity for patients who had Ravitch repair was significantly lower (SMD, 0.71 [CI -1.06, -0.36]; I2 = 19.6%) than preoperative. Based on 2 studies after removal of the Nuss bar, FEV1 was significantly increased from preoperative values (SMD, 0.39 [CI, 0.03, 0.74]; I2 = 0%). Stroke volume increased after surgery (SMD, 0.40 [CI, 0.10, 0.70]; I2 = 0%) after Ravitch repair. There was a trend toward improved exercise tolerance, but it was not statistically significant. Conclusions: Total lung capacity was decreased after Ravitch repair, and FEV1 was increased after Nuss bar removal. Stroke volume may be increased after Ravitch repair. Exercise tolerance was not improved after either type of surgical repair.
AB - Objective: We performed a review of current data to determine the effect that operation has on pulmonary function, aerobic capacity, and stroke volume in patients with pectus excavatum. Study design: Two reviewers independently assessed clinical trials and collected data on interventions and outcomes. To qualify for inclusion, a study had to include preoperative and postoperative assessment, provide outcomes in either a published percentile or qualified matched control form to control for interval growth, and include only original patient groups. Results: Postoperative total lung capacity for patients who had Ravitch repair was significantly lower (SMD, 0.71 [CI -1.06, -0.36]; I2 = 19.6%) than preoperative. Based on 2 studies after removal of the Nuss bar, FEV1 was significantly increased from preoperative values (SMD, 0.39 [CI, 0.03, 0.74]; I2 = 0%). Stroke volume increased after surgery (SMD, 0.40 [CI, 0.10, 0.70]; I2 = 0%) after Ravitch repair. There was a trend toward improved exercise tolerance, but it was not statistically significant. Conclusions: Total lung capacity was decreased after Ravitch repair, and FEV1 was increased after Nuss bar removal. Stroke volume may be increased after Ravitch repair. Exercise tolerance was not improved after either type of surgical repair.
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U2 - 10.1016/j.jpeds.2008.03.037
DO - 10.1016/j.jpeds.2008.03.037
M3 - Article
C2 - 18534622
AN - SCOPUS:49349112683
SN - 0022-3476
VL - 153
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 3
ER -