Cardiorespiratory Function after Operation for Pectus Excavatum

Jonathan N. Johnson, Tyler K. Hartman, Paolo Pianosi, David J. Driscoll

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


Objective: We performed a review of current data to determine the effect that operation has on pulmonary function, aerobic capacity, and stroke volume in patients with pectus excavatum. Study design: Two reviewers independently assessed clinical trials and collected data on interventions and outcomes. To qualify for inclusion, a study had to include preoperative and postoperative assessment, provide outcomes in either a published percentile or qualified matched control form to control for interval growth, and include only original patient groups. Results: Postoperative total lung capacity for patients who had Ravitch repair was significantly lower (SMD, 0.71 [CI -1.06, -0.36]; I2 = 19.6%) than preoperative. Based on 2 studies after removal of the Nuss bar, FEV1 was significantly increased from preoperative values (SMD, 0.39 [CI, 0.03, 0.74]; I2 = 0%). Stroke volume increased after surgery (SMD, 0.40 [CI, 0.10, 0.70]; I2 = 0%) after Ravitch repair. There was a trend toward improved exercise tolerance, but it was not statistically significant. Conclusions: Total lung capacity was decreased after Ravitch repair, and FEV1 was increased after Nuss bar removal. Stroke volume may be increased after Ravitch repair. Exercise tolerance was not improved after either type of surgical repair.

Original languageEnglish (US)
JournalJournal of Pediatrics
Issue number3
StatePublished - Sep 1 2008
Externally publishedYes


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