Cardiopulmonary bypass and cardioplegia

Gabriel Loor, J. Ernesto Molina

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter describes the history and techniques of cardiopulmonary bypass, a process that effectually excludes the heart from the general circulation and leaves it empty so that it can accommodate open cardiac surgical intervention. Since its first implementation, cardiopulmonary bypass has improved significantly to become a very highly sophisticated, but reliably performed procedure. The near future promises even more improvements because research and innovations continue to make cardiac operations safer and more efficient. With the advent of coronary bypass in the late 1960s and early 1970s, surgeons became increasingly interested in finding ways to protect the heart during the period of global ischemia via infusion of cold perfusates into the coronary circulation (i.e., cardioplegia). Therefore, this chapter further details the advantages and disadvantages of various cardioplegia solutions which have been developed at several separate institutions, including extracellular-and intracellular-type solutions.

Original languageEnglish (US)
Title of host publicationHandbook of Cardiac Anatomy, Physiology, and Devices, Third Edition
PublisherSpringer International Publishing
Number of pages20
ISBN (Electronic)9783319194646
ISBN (Print)9783319194639
StatePublished - Jan 1 2015

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2015.


  • Anticoagulation
  • Cardioplegia
  • Cardiopulmonary bypass
  • Cross-circulation
  • Heart-lung machine


Dive into the research topics of 'Cardiopulmonary bypass and cardioplegia'. Together they form a unique fingerprint.

Cite this