Cardio-oncology in the older adult

Prajwal Reddy; Chetan Shenoy; Anne H. Blaes

doi:10.1016/j.jgo.2017.04.001

Cardio-oncology in the older adult

Prajwal Reddy, Chetan Shenoy, Anne H. Blaes

Research output: Contribution to journal › Review article › peer-review

27 Scopus citations

Abstract

Heart disease and cancer are the leading causes of death in older adults. Many first-line cancer treatments have the potential for cardiotoxicity. Age-related risk factors, pre-existing cardiac disease, and a high prevalence of comorbidities are reasons for increased cardiotoxicity in older adults. Concerns regarding cardiotoxicity may lead to frailty bias and undertreatment, resulting in suboptimal outcomes. There is an urgent need for geriatric-specific evidence and guidelines to help tailor care for this vulnerable group. A multi-disciplinary approach based on close collaboration between oncologists, cardiologists, and geriatricians, among other specialist clinicians is essential.

Original language	English (US)
Pages (from-to)	308-314
Number of pages	7
Journal	Journal of Geriatric Oncology
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/j.jgo.2017.04.001
State	Published - Jul 2017

Bibliographical note

Funding Information:
This article was supported by the National Institutes of Health grant K23HL132011-01 and the University of Minnesota Clinical and Translational Science Institute KL2 Scholars Career Development Program Award (National Institutes of Health grant KL2TR000113-05), both to Dr. Chetan Shenoy.

Publisher Copyright:
© 2017 Elsevier Inc.

Keywords

Cardio-oncology
Cardiotoxic treatments
Cardiotoxicity
Geriatrics
Older adult

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jgo.2017.04.001

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776715

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title = "Cardio-oncology in the older adult",

abstract = "Heart disease and cancer are the leading causes of death in older adults. Many first-line cancer treatments have the potential for cardiotoxicity. Age-related risk factors, pre-existing cardiac disease, and a high prevalence of comorbidities are reasons for increased cardiotoxicity in older adults. Concerns regarding cardiotoxicity may lead to frailty bias and undertreatment, resulting in suboptimal outcomes. There is an urgent need for geriatric-specific evidence and guidelines to help tailor care for this vulnerable group. A multi-disciplinary approach based on close collaboration between oncologists, cardiologists, and geriatricians, among other specialist clinicians is essential.",

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note = "Funding Information: This article was supported by the National Institutes of Health grant K23HL132011-01 and the University of Minnesota Clinical and Translational Science Institute KL2 Scholars Career Development Program Award (National Institutes of Health grant KL2TR000113-05), both to Dr. Chetan Shenoy. Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

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AU - Shenoy, Chetan

AU - Blaes, Anne H.

N1 - Funding Information: This article was supported by the National Institutes of Health grant K23HL132011-01 and the University of Minnesota Clinical and Translational Science Institute KL2 Scholars Career Development Program Award (National Institutes of Health grant KL2TR000113-05), both to Dr. Chetan Shenoy. Publisher Copyright: © 2017 Elsevier Inc.

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N2 - Heart disease and cancer are the leading causes of death in older adults. Many first-line cancer treatments have the potential for cardiotoxicity. Age-related risk factors, pre-existing cardiac disease, and a high prevalence of comorbidities are reasons for increased cardiotoxicity in older adults. Concerns regarding cardiotoxicity may lead to frailty bias and undertreatment, resulting in suboptimal outcomes. There is an urgent need for geriatric-specific evidence and guidelines to help tailor care for this vulnerable group. A multi-disciplinary approach based on close collaboration between oncologists, cardiologists, and geriatricians, among other specialist clinicians is essential.

AB - Heart disease and cancer are the leading causes of death in older adults. Many first-line cancer treatments have the potential for cardiotoxicity. Age-related risk factors, pre-existing cardiac disease, and a high prevalence of comorbidities are reasons for increased cardiotoxicity in older adults. Concerns regarding cardiotoxicity may lead to frailty bias and undertreatment, resulting in suboptimal outcomes. There is an urgent need for geriatric-specific evidence and guidelines to help tailor care for this vulnerable group. A multi-disciplinary approach based on close collaboration between oncologists, cardiologists, and geriatricians, among other specialist clinicians is essential.

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KW - Cardiotoxic treatments

KW - Cardiotoxicity

KW - Geriatrics

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Cardio-oncology in the older adult

Abstract

Bibliographical note

Keywords

UN SDGs

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