Cardiac tissue engineering: A pathway for repair

Rebecca Hortensius; Wei Han Lin; Brenda M. Ogle

doi:10.1016/B978-0-12-813068-1.00001-4

Cardiac tissue engineering: A pathway for repair

Rebecca Hortensius, Wei Han Lin, Brenda M. Ogle

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

Cardiovascular disease (CVD) is the leading cause of death globally, accounting for 31.5% of deaths worldwide. The widespread (and growing) prevalence of CVD and the inadequacy of the adult human heart to regenerate on its own after a major ischemic event calls for the development of tissue regeneration strategies to facilitate and support cardiomyocyte maturation and function in vivo. This chapter explores regenerative therapies of graded levels of complexity beginning with cell transplantation and ending with a full thickness graft with perfusable vasculature.

Original language	English (US)
Title of host publication	Engineering in Medicine
Subtitle of host publication	Advances and Challenges
Publisher	Elsevier
Pages	3-33
Number of pages	31
ISBN (Electronic)	9780128130681
ISBN (Print)	9780128135143
DOIs	https://doi.org/10.1016/B978-0-12-813068-1.00001-4
State	Published - Jan 1 2018

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc. All rights reserved.

Keywords

3D bioprinting
Cardiac muscle repair
Cardiac tissue bioengineering
Cardiac tissue regeneration
Cardiomyocyte transplantation
Stem cell therapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-12-813068-1.00001-4

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title = "Cardiac tissue engineering: A pathway for repair",

abstract = "Cardiovascular disease (CVD) is the leading cause of death globally, accounting for 31.5% of deaths worldwide. The widespread (and growing) prevalence of CVD and the inadequacy of the adult human heart to regenerate on its own after a major ischemic event calls for the development of tissue regeneration strategies to facilitate and support cardiomyocyte maturation and function in vivo. This chapter explores regenerative therapies of graded levels of complexity beginning with cell transplantation and ending with a full thickness graft with perfusable vasculature.",

keywords = "3D bioprinting, Cardiac muscle repair, Cardiac tissue bioengineering, Cardiac tissue regeneration, Cardiomyocyte transplantation, Stem cell therapy",

author = "Rebecca Hortensius and Lin, {Wei Han} and Ogle, {Brenda M.}",

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T2 - A pathway for repair

AU - Hortensius, Rebecca

AU - Lin, Wei Han

AU - Ogle, Brenda M.

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Y1 - 2018/1/1

N2 - Cardiovascular disease (CVD) is the leading cause of death globally, accounting for 31.5% of deaths worldwide. The widespread (and growing) prevalence of CVD and the inadequacy of the adult human heart to regenerate on its own after a major ischemic event calls for the development of tissue regeneration strategies to facilitate and support cardiomyocyte maturation and function in vivo. This chapter explores regenerative therapies of graded levels of complexity beginning with cell transplantation and ending with a full thickness graft with perfusable vasculature.

AB - Cardiovascular disease (CVD) is the leading cause of death globally, accounting for 31.5% of deaths worldwide. The widespread (and growing) prevalence of CVD and the inadequacy of the adult human heart to regenerate on its own after a major ischemic event calls for the development of tissue regeneration strategies to facilitate and support cardiomyocyte maturation and function in vivo. This chapter explores regenerative therapies of graded levels of complexity beginning with cell transplantation and ending with a full thickness graft with perfusable vasculature.

KW - 3D bioprinting

KW - Cardiac muscle repair

KW - Cardiac tissue bioengineering

KW - Cardiac tissue regeneration

KW - Cardiomyocyte transplantation

KW - Stem cell therapy

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DO - 10.1016/B978-0-12-813068-1.00001-4

M3 - Chapter

AN - SCOPUS:85083247218

SN - 9780128135143

SP - 3

EP - 33

BT - Engineering in Medicine

PB - Elsevier

ER -

Cardiac tissue engineering: A pathway for repair

Abstract

Bibliographical note

Keywords

UN SDGs

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