Cardiac septal defects: Treatment via the amplatzer ® family of devices

Research output: Chapter in Book/Report/Conference proceedingChapter


The majority of patients with congenital heart disease present with defects resulting from vascular narrowing or absence (such as interruption or coarctation of the aorta or pulmonary arteries) or failure of structures to fuse or separate during development (total anomalous pulmonary venous connection, septal defects, fusion of valve cusps).Correction of these defects initially began with open-heart surgery, but now many of these repairs can be performed through catheter-delivered closure devices (e.g., Amplatzer closure devices). This chapter will present a brief history of defect repairs and provide information on the design, development, and preclinical animal testing of such systems.

Original languageEnglish (US)
Title of host publicationHandbook of Cardiac Anatomy, Physiology, and Devices, Third Edition
PublisherSpringer International Publishing
Number of pages14
ISBN (Electronic)9783319194646
ISBN (Print)9783319194639
StatePublished - Jan 1 2015


  • Atrial septal defect
  • Interventional cardiac catheterization
  • Muscular ventricular septal defect
  • Patent ductus arteriosus
  • Perimembranous ventricular septal defect
  • Transcatheter closure


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