Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN

Bingfang Zhang; Subat Turdi; Quan Li; Faye L. Lopez; Anna R. Eason; Piero Anversa; Jun Ren

doi:10.1016/j.freeradbiomed.2010.07.020

Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN

Bingfang Zhang
, Subat Turdi
, Quan Li
, Faye L. Lopez
, Anna R. Eason
, Piero Anversa
, Jun Ren

Epidemiology & Community Health

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Original language	English (US)
Pages (from-to)	1238-1253
Number of pages	16
Journal	Free Radical Biology and Medicine
Volume	49
Issue number	7
DOIs	https://doi.org/10.1016/j.freeradbiomed.2010.07.020 https://doi.org/10.1016/j.freeradbiomed.2010.07.020
State	Published - 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Alcohol, Cardiac hypertrophy, Contractile function, Intracellular Ca, Akt, mTOR, GSK3β, Foxo3a, Free radicals

Publisher link

http://www.sciencedirect.com/science/article/pii/S0891584910004466

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Cite this

Zhang, B., Turdi, S., Li, Q., Lopez, F. L., Eason, A. R., Anversa, P., & Ren, J. (2010). Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN. Free Radical Biology and Medicine, 49(7), 1238-1253. https://doi.org/10.1016/j.freeradbiomed.2010.07.020, https://doi.org/10.1016/j.freeradbiomed.2010.07.020

Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN. / Zhang, Bingfang; Turdi, Subat; Li, Quan et al.
In: Free Radical Biology and Medicine, Vol. 49, No. 7, 2010, p. 1238-1253.

Research output: Contribution to journal › Article › peer-review

Zhang, B, Turdi, S, Li, Q, Lopez, FL, Eason, AR, Anversa, P & Ren, J 2010, 'Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN', Free Radical Biology and Medicine, vol. 49, no. 7, pp. 1238-1253. https://doi.org/10.1016/j.freeradbiomed.2010.07.020, https://doi.org/10.1016/j.freeradbiomed.2010.07.020

Zhang B, Turdi S, Li Q, Lopez FL, Eason AR, Anversa P et al. Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN. Free Radical Biology and Medicine. 2010;49(7):1238-1253. doi: 10.1016/j.freeradbiomed.2010.07.020, 10.1016/j.freeradbiomed.2010.07.020

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