Carboplatin-associated Cranial Neuropathy

Shanlee M. Stevens, Collin M. McClelland, John E. Trusheim, Michael S. Lee

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Carboplatin is a platinum-based chemotherapeutic agent used for the treatment of many solid tumors. Peripheral neuropathy is a common side effect; but, to our knowledge, ocular motor cranial neuropathies have not been reported in the literature. We describe a case of persistent third and fourth nerve palsies after systemic administration of intra-arterial carboplatin for glioblastoma multiforme. Neither nerve regained function after carboplatin was stopped.

Original languageEnglish (US)
Pages (from-to)302-305
Number of pages4
JournalNeuro-Ophthalmology
Volume42
Issue number5
DOIs
StatePublished - Sep 3 2018

Bibliographical note

Publisher Copyright:
© 2018, © 2018 The Authors.

Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.

Keywords

  • Carboplatin
  • cranial neuropathy
  • glioblastoma

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