Carbon nanotubes swine influenza (H1N1) virus sensors

Dongjin Lee, Yogesh Chander, Sagar M. Goyal, Tianhong Cui

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a label-free detection of swine influenza virus (SIV) H1N1 by means of the excellent electrical properties of single-walled carbon nanotubes (SWCNTs). The electrical resistance of SWCNT resistor tends to increase upon the surface adsorption of macromolecules such as poly-L-lysine, anti-SIV antibodies, and SIVs in the process of immunoassay. The SWCNT network resistor was successfully able to detect as low as 180 TCID50/ml of SIV using the resistance shifts upon immunobinding of SIVs. The sensor specificity was demonstrated against transmissible gastroenteritis virus (TGEV) and feline calicivirus (FCV). This facile CNT-based immnoassay has potential applications as a rapid point-of-care detection or a sensing platform for lab-on-a-chip systems.

Original languageEnglish (US)
Title of host publicationASME 2010 International Mechanical Engineering Congress and Exposition, IMECE 2010
Pages49-52
Number of pages4
DOIs
StatePublished - Dec 1 2010
EventASME 2010 International Mechanical Engineering Congress and Exposition, IMECE 2010 - Vancouver, BC, Canada
Duration: Nov 12 2010Nov 18 2010

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume2

Other

OtherASME 2010 International Mechanical Engineering Congress and Exposition, IMECE 2010
Country/TerritoryCanada
CityVancouver, BC
Period11/12/1011/18/10

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