CAR-T for multiple myeloma: practice pearls

Daniel O’Leary; Veronika Bachanova

doi:10.1038/s41409-025-02582-6

CAR-T for multiple myeloma: practice pearls

Medicine - Hematology, Oncology, Transplant

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

The CAR-T cell products ciltacabtagene autoleucel and idecabtagene vicleucel have transformed the management of patients with multiple myeloma. Here, we present a practical guide highlighting clinical pearls on the incorporation of CAR-T into clinical practice. Topics addressed include expected outcomes, recommendations for referral timing, bridging therapy, treatment complications, therapeutic sequencing, and management of relapse.

Original language	English (US)
Pages (from-to)	940-947
Number of pages	8
Journal	Bone marrow transplantation
Volume	60
Issue number	7
DOIs	https://doi.org/10.1038/s41409-025-02582-6
State	Published - Jul 2025

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© The Author(s), under exclusive licence to Springer Nature Limited 2025.

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Journal Article
Review

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10.1038/s41409-025-02582-6

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abstract = "The CAR-T cell products ciltacabtagene autoleucel and idecabtagene vicleucel have transformed the management of patients with multiple myeloma. Here, we present a practical guide highlighting clinical pearls on the incorporation of CAR-T into clinical practice. Topics addressed include expected outcomes, recommendations for referral timing, bridging therapy, treatment complications, therapeutic sequencing, and management of relapse.",

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AB - The CAR-T cell products ciltacabtagene autoleucel and idecabtagene vicleucel have transformed the management of patients with multiple myeloma. Here, we present a practical guide highlighting clinical pearls on the incorporation of CAR-T into clinical practice. Topics addressed include expected outcomes, recommendations for referral timing, bridging therapy, treatment complications, therapeutic sequencing, and management of relapse.

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UR - https://www.scopus.com/pages/publications/105002760876#tab=citedBy

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CAR-T for multiple myeloma: practice pearls

Abstract

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