CAR-T for multiple myeloma: practice pearls

Daniel O’Leary; Veronika Bachanova

doi:10.1038/s41409-025-02582-6

CAR-T for multiple myeloma: practice pearls

Daniel O’Leary, Veronika Bachanova

Medicine - Hematology, Oncology, Transplant

Research output: Contribution to journal › Review article › peer-review

Abstract

The CAR-T cell products ciltacabtagene autoleucel and idecabtagene vicleucel have transformed the management of patients with multiple myeloma. Here, we present a practical guide highlighting clinical pearls on the incorporation of CAR-T into clinical practice. Topics addressed include expected outcomes, recommendations for referral timing, bridging therapy, treatment complications, therapeutic sequencing, and management of relapse.

Original language	English (US)
Article number	101095
Journal	Bone marrow transplantation
DOIs	https://doi.org/10.1038/s41409-025-02582-6
State	Accepted/In press - 2025

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive licence to Springer Nature Limited 2025.

PubMed: MeSH publication types

Journal Article
Review

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10.1038/s41409-025-02582-6

Cite this

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abstract = "The CAR-T cell products ciltacabtagene autoleucel and idecabtagene vicleucel have transformed the management of patients with multiple myeloma. Here, we present a practical guide highlighting clinical pearls on the incorporation of CAR-T into clinical practice. Topics addressed include expected outcomes, recommendations for referral timing, bridging therapy, treatment complications, therapeutic sequencing, and management of relapse.",

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AB - The CAR-T cell products ciltacabtagene autoleucel and idecabtagene vicleucel have transformed the management of patients with multiple myeloma. Here, we present a practical guide highlighting clinical pearls on the incorporation of CAR-T into clinical practice. Topics addressed include expected outcomes, recommendations for referral timing, bridging therapy, treatment complications, therapeutic sequencing, and management of relapse.

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CAR-T for multiple myeloma: practice pearls

Abstract

Bibliographical note

PubMed: MeSH publication types

Publisher link

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