Capillary Basement Membranes and Diabetes Mellitus

Douglas G. Rogers, Niels Juel Christensen, Michael W Steffes, David E.r. Sutherland, Frederick C. Goetz, Stephen S. Rich, Michael Mauer

Research output: Contribution to journalLetter

Abstract

To the Editor: Steffes et al. (May 16 issue) have recently documented that morphologic changes in renal tissue of patients with chronic insulin-dependent diabetes (IDD) do not occur in the nondiabetic identical twins of these patients.1 This finding provides further evidence that the microvascular disease seen in IDD is secondary to the metabolic derangements of the diabetic state, and not an isolated, foregone genetic conclusion. The authors wisely do not attempt to identify these metabolic derangements. Their failure to show a correlation between increased muscle capillary basement membrane width and fractional mesangial volume is disappointing. However, this apparent lack of.

Original languageEnglish (US)
Pages (from-to)1024-1025
Number of pages2
JournalNew England Journal of Medicine
Volume313
Issue number16
DOIs
StatePublished - Oct 17 1985

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Basement Membrane
Diabetes Mellitus
Insulin
Monozygotic Twins
Kidney
Muscles

Cite this

Rogers, D. G., Christensen, N. J., Steffes, M. W., Sutherland, D. E. R., Goetz, F. C., Rich, S. S., & Mauer, M. (1985). Capillary Basement Membranes and Diabetes Mellitus. New England Journal of Medicine, 313(16), 1024-1025. https://doi.org/10.1056/NEJM198510173131615

Capillary Basement Membranes and Diabetes Mellitus. / Rogers, Douglas G.; Christensen, Niels Juel; Steffes, Michael W; Sutherland, David E.r.; Goetz, Frederick C.; Rich, Stephen S.; Mauer, Michael.

In: New England Journal of Medicine, Vol. 313, No. 16, 17.10.1985, p. 1024-1025.

Research output: Contribution to journalLetter

Rogers, DG, Christensen, NJ, Steffes, MW, Sutherland, DER, Goetz, FC, Rich, SS & Mauer, M 1985, 'Capillary Basement Membranes and Diabetes Mellitus', New England Journal of Medicine, vol. 313, no. 16, pp. 1024-1025. https://doi.org/10.1056/NEJM198510173131615
Rogers DG, Christensen NJ, Steffes MW, Sutherland DER, Goetz FC, Rich SS et al. Capillary Basement Membranes and Diabetes Mellitus. New England Journal of Medicine. 1985 Oct 17;313(16):1024-1025. https://doi.org/10.1056/NEJM198510173131615
Rogers, Douglas G. ; Christensen, Niels Juel ; Steffes, Michael W ; Sutherland, David E.r. ; Goetz, Frederick C. ; Rich, Stephen S. ; Mauer, Michael. / Capillary Basement Membranes and Diabetes Mellitus. In: New England Journal of Medicine. 1985 ; Vol. 313, No. 16. pp. 1024-1025.
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