Canine mandibular osteosarcoma: 51 cases (1980-1992)

Rodney C. Straw, Barbara E. Powers, Jeffrey Klausner, Ralph A. Henderson, Wallace B. Morrison, Dudley L. McCaw, H. Jay Harvey, Robert M. Jacobs, R. John Berg

Research output: Contribution to journalArticlepeer-review

77 Scopus citations

Abstract

Fifty-one dogs treated for mandibular osteosarcomas (OSs) were studied retrospectively. Treatments were partial mandibulectomy (n=32); partial mandibulectomy and chemotherapy (n=10); partial mandibulectomy and radiation therapy (n=3); partial mandibulectomy, radiation therapy, and chemotherapy (n=4); and radiation therapy alone (n=2). The overall one-year survival rate was 59.3%. Dogs treated with surgery alone had a one-year survival rate of 71%, which is higher than the one-year survival rate for dogs with appendicular OSs treated with surgery alone (p of 0.001 or less; hazard ratio of 0.29). There was no apparent effect of various treatment modalities, nor institution where treatment was given, nor histological type. Histological score and, to a lesser extent, histological grade were predictive of survival outcome.

Original languageEnglish (US)
Pages (from-to)257-262
Number of pages6
JournalJournal of the American Animal Hospital Association
Volume32
Issue number3
DOIs
StatePublished - 1996

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