Canine cystine urolithiasis: Cause, detection, treatment, and prevention

C. A. Osborne, S. L. Sanderson, J. P. Lulich, J. W. Bartges, L. K. Ulrich, L. A. Koehler, K. A. Bird, L. L. Swanson

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations


Cystine uroliths are a sequela t cystinuria, an inherited renal tubular defect in reabsorption of cystine and some other amino acids. At the Minnesota Urolith Center, 67 breeds of dogs, were identified, including English Bulldogs, Dachshunds, Mastiffs, and Newfoundlands. In some dogs, the severity of cystinuria may decline with advancing age. Current recommendations for dissolution of cystine uroliths include various combinations of diet modification, diuresis, administration of 2-MPG, and alkalinization of urine.

Original languageEnglish (US)
Pages (from-to)193-211
Number of pages19
JournalVeterinary Clinics of North America - Small Animal Practice
Issue number1
StatePublished - 1999

Bibliographical note

Funding Information:
This study was supported, in part, by a grant from Hill's Pet Nutrition (Topeka, KS).


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