Cancer immunotherapy based on the killing of Salmonella typhimurium-infected tumour cells

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

The use of bacteria for anticancer purposes was first attempted over 100 years ago. Recently, several strains of Salmonella have been shown to possess anticancer activity and, interestingly. Salmonella possesses a unique propensity to track to tumour tissue in vivo. This review presents the use of Salmonella for cancer immunotherapy, including the distinguishing characteristics of this organism and preclinical as well as clinical data.

Original languageEnglish (US)
Pages (from-to)443-449
Number of pages7
JournalExpert opinion on biological therapy
Volume5
Issue number4
DOIs
StatePublished - Apr 1 2005

Keywords

  • Cancer
  • Immunotherapy
  • Salmonella

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