Abstract
A facile one-pot, four-component synthesis of biologically important benzylpyrazolyl coumarins in water has been demonstrated using environmentally benign Ca(II) as the catalyst. Participation of aliphatic aldehydes has been described for the first time. Short reaction times, high yields and chromatography free isolation of the products, usage of eco-friendly catalyst and solvent are the key features of this method.
Original language | English (US) |
---|---|
Pages (from-to) | 4770-4774 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 56 |
Issue number | 33 |
DOIs | |
State | Published - Jul 13 2015 |
Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2015 Elsevier Ltd. All rights reserved.
Keywords
- Benzylpyrazolylcoumarins
- Ca(II) catalysis
- Green synthesis
- Heterocyclic compounds
- Multicomponent reactions
- One-pot reaction