Ca(II)-catalyzed, one-pot four component synthesis of functionally embellished benzylpyrazolyl coumarins in water

Srinivasarao Yaragorla; Abhishek Pareek; Ravikrishna Dada

doi:10.1016/j.tetlet.2015.06.049

Ca(II)-catalyzed, one-pot four component synthesis of functionally embellished benzylpyrazolyl coumarins in water

Srinivasarao Yaragorla, Abhishek Pareek, Ravikrishna Dada

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

A facile one-pot, four-component synthesis of biologically important benzylpyrazolyl coumarins in water has been demonstrated using environmentally benign Ca(II) as the catalyst. Participation of aliphatic aldehydes has been described for the first time. Short reaction times, high yields and chromatography free isolation of the products, usage of eco-friendly catalyst and solvent are the key features of this method.

Original language	English (US)
Pages (from-to)	4770-4774
Number of pages	5
Journal	Tetrahedron Letters
Volume	56
Issue number	33
DOIs	https://doi.org/10.1016/j.tetlet.2015.06.049
State	Published - Jul 13 2015
Externally published	Yes

Bibliographical note

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© 2015 Elsevier Ltd. All rights reserved.

Keywords

Benzylpyrazolylcoumarins
Ca(II) catalysis
Green synthesis
Heterocyclic compounds
Multicomponent reactions
One-pot reaction

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10.1016/j.tetlet.2015.06.049

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abstract = "A facile one-pot, four-component synthesis of biologically important benzylpyrazolyl coumarins in water has been demonstrated using environmentally benign Ca(II) as the catalyst. Participation of aliphatic aldehydes has been described for the first time. Short reaction times, high yields and chromatography free isolation of the products, usage of eco-friendly catalyst and solvent are the key features of this method.",

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AU - Yaragorla, Srinivasarao

AU - Pareek, Abhishek

AU - Dada, Ravikrishna

PY - 2015/7/13

Y1 - 2015/7/13

N2 - A facile one-pot, four-component synthesis of biologically important benzylpyrazolyl coumarins in water has been demonstrated using environmentally benign Ca(II) as the catalyst. Participation of aliphatic aldehydes has been described for the first time. Short reaction times, high yields and chromatography free isolation of the products, usage of eco-friendly catalyst and solvent are the key features of this method.

AB - A facile one-pot, four-component synthesis of biologically important benzylpyrazolyl coumarins in water has been demonstrated using environmentally benign Ca(II) as the catalyst. Participation of aliphatic aldehydes has been described for the first time. Short reaction times, high yields and chromatography free isolation of the products, usage of eco-friendly catalyst and solvent are the key features of this method.

KW - Benzylpyrazolylcoumarins

KW - Ca(II) catalysis

KW - Green synthesis

KW - Heterocyclic compounds

KW - Multicomponent reactions

KW - One-pot reaction

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M3 - Article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 33

ER -

Ca(II)-catalyzed, one-pot four component synthesis of functionally embellished benzylpyrazolyl coumarins in water

Abstract

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Keywords

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