Building co-crystals with molecular sense and supramolecular sensibility

Christer B. Aakeröy, Debra J. Salmon

Research output: Contribution to journalReview articlepeer-review

710 Scopus citations


Molecular recognition is typically associated with molecules in solution, but such events are also responsible for organizing molecules in the solid state. Translating principles of molecular recognition to solid-state assembly of heteromeric molecular solids is of key importance to the development of versatile, reliable and practical supramolecular synthesis. In this article we provide an overview of some modular and transferable strategies for the synthesis of binary and ternary supermolecules and co-crystals based upon a hierarchy of intermolecular interactions, notably hydrogen bonds.

Original languageEnglish (US)
Pages (from-to)439-448
Number of pages10
StatePublished - Jul 4 2005
Externally publishedYes


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