Abstract
Brownian dynamics simulations of a DNA molecule in the electroosmotic flow were performed. This allows to assess the effectiveness of these flows in stretching polymers, and to probe the aforementioned issues of polymer dynamics in flows with an inhomogeneous velocity gradient and the competition between electrophoresis and electroosmosis. This paper aims to use Brownian dynamics simulations to study the stretching and transport of DNA in a complex electroosmotic flow that can be generated in a microfluidic device.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 925-936 |
| Number of pages | 12 |
| Journal | Journal of Chemical Physics |
| Volume | 118 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 8 2003 |