Broadening the Scope of the Zwitterionic 1,3-Diaza-Claisen Rearrangement through a Tethering Strategy

Keyphrases

• Carbodiimide 100%
• Zwitterion 100%
• Claisen Rearrangement 100%
• Allylic Amines 60%
• Deuterium 40%
• Deuterium Labeling 40%
• Ionic Mechanism 40%
• Silver Salt 40%
• Allylic 40%
• Deuteration 20%
• Density Functional Calculations 20%
• C-N Bond 20%
• Silica Gel 20%
• Sigmatropic 20%
• Zwitterionic Intermediate 20%
• Allyl Group 20%
• Reactivity Trends 20%
• Et3N 20%
• Bridged Bicyclic 20%
• Intramolecular Cyclization 20%
• Sigmatropic Rearrangement 20%
• Heterolytic Cleavage 20%
• AgOTf 20%
• Isothiourea 20%
• Salt Contamination 20%
• Silver-free 20%
• Allyl Cation 20%

Chemistry

• Carbodiimide 100%
• Claisen Rearrangement 100%
• Deuterium 80%
• Zwitterion 60%
• Amine 60%
• Silver Salt 40%
• Silver 20%
• Allyl Group 20%
• Intramolecular Cyclization 20%
• Density Functional Theory 20%
• Heterolytic Cleavage 20%
• Cation 20%