TY - JOUR
T1 - Brief report
T2 - Molecular characterization of a novel reassorted pandemic H1N1 2009 in Thai pigs
AU - Kitikoon, Pravina
AU - Sreta, Donruethai
AU - Nuntawan Na Ayudhya, Suparlark
AU - Wongphatcharachai, Manoosak
AU - Lapkuntod, Jiradej
AU - Prakairungnamthip, Duangduean
AU - Bunpapong, Napawan
AU - Suradhat, Sanipa
AU - Thanawongnuwech, Roongroje
AU - Amonsin, Alongkorn
PY - 2011/8/1
Y1 - 2011/8/1
N2 - For the past 10 years, endemic swine influenza H1 viruses in Thailand have been characterized as reassortants of swine virus genes from swine influenza viruses (SIV) in US and European pigs. Here the authors report the emergence of a novel reassorted H1N1 (rH1N1) virus consisted of human, avian, and swine virus genes from the pandemic H1N1 2009 (pH1N1) virus with a neuraminidase (NA) gene from a Thai swine H1N1 (ThH1N1) isolate. The rH1N1 virus was detected in nursery pigs during a respiratory disease outbreak in central Thailand in early 2010. The rH1N1 virus was repeatedly isolated from infected pigs, suggesting that it can transmit efficiently among the pig population. The appearance of rH1N1 virus in the field occurred within months of the introduction of pH1N1 virus into the Thai swine population in late 2009. The finding highlights the role of pig in generating newly reassorted influenza A viruses and also the significance of continuing disease surveillance and genetic characterization of SIV in pigs.
AB - For the past 10 years, endemic swine influenza H1 viruses in Thailand have been characterized as reassortants of swine virus genes from swine influenza viruses (SIV) in US and European pigs. Here the authors report the emergence of a novel reassorted H1N1 (rH1N1) virus consisted of human, avian, and swine virus genes from the pandemic H1N1 2009 (pH1N1) virus with a neuraminidase (NA) gene from a Thai swine H1N1 (ThH1N1) isolate. The rH1N1 virus was detected in nursery pigs during a respiratory disease outbreak in central Thailand in early 2010. The rH1N1 virus was repeatedly isolated from infected pigs, suggesting that it can transmit efficiently among the pig population. The appearance of rH1N1 virus in the field occurred within months of the introduction of pH1N1 virus into the Thai swine population in late 2009. The finding highlights the role of pig in generating newly reassorted influenza A viruses and also the significance of continuing disease surveillance and genetic characterization of SIV in pigs.
KW - Influenza
KW - Pandemic H1N1 2009
KW - Reassort
KW - Swine
KW - Thailand
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U2 - 10.1007/s11262-011-0597-5
DO - 10.1007/s11262-011-0597-5
M3 - Article
C2 - 21442301
AN - SCOPUS:79952986750
VL - 43
SP - 1
EP - 5
JO - Virus Genes
JF - Virus Genes
SN - 0920-8569
IS - 1
ER -