Ronald A. Siegel, Larry Brown, Elazer R. Edelman, Robert J. Linhardt

Research output: Contribution to journalArticlepeer-review


The Hebrew word “b'reshith” (בְּרֵאשִׁית) means “in the beginning”. It is the first word and title of the Book of Genesis, and it describes a process of creation. The four authors were present at the beginning of Langer labs, and the purpose of this essay is to convey the scientific and technological zeitgeist that existed in the late 1970s and early 1980s, when Bob Langer began his exceptionally creative work. While Langer labs has branched into many other areas, Bob's unique ability to recognize important problems and entice people to look beyond their own disciplines to solve them was evident from the start. We focus on the two areas of most interest to Bob at the time, namely controlled release of macromolecules from polymers, and removal of heparin in order to prevent uncontrolled bleeding during surgery.

Original languageEnglish (US)
Pages (from-to)252-257
Number of pages6
JournalJournal of Controlled Release
StatePublished - Sep 10 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier B.V.


  • Early days
  • Langer labs


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