Breath-odor evaluation by detection of volatile sulfur compounds--correlation with organoleptic odor ratings.

Catherine M. Hunter, Hollandra P. Niles, Patricia A. Lenton, Georgia J. Majerus, Joe Vazquez, Clifford Kloos, Ravi Subramanyam, Malcolm I. Williams, Diane Cummins

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Volatile sulfur compounds are known to be major contributors to oral malodor, and their detection by gas chromatography (GC) is a commonly used method for evaluating breath odor in clinical trials. A custom-designed breath-sampling GC system was developed for this purpose. A clinical study was performed to compare the performance of this instrumental method to organoleptic evaluation by trained odor judges. A statistically significant correlation was found between the measured levels of volatile sulfurs and the ratings of the odor judges. Both methods performed similarly in evaluating the breath-freshening effects of two test products. These results demonstrate the strength of the GC method for evaluating breath odor and predicting the breath-freshening effects of oral-care products.

Original languageEnglish (US)
Pages (from-to)25-28; quiz 43
JournalCompendium of continuing education in dentistry (Jamesburg, N.J. : 1995)
Volume24
Issue number9 Suppl
StatePublished - Sep 2003

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