It has been suggested that pediatric patients treated with spinal irradiation may have an elevated risk of breast cancer. Among a cohort of 363 long-term survivors of a pediatric central nervous system tumor or leukemia treated with spinal irradiation, there was little evidence of an increased breast cancer risk.
Bibliographical noteFunding Information:
This work was supported by the National Cancer Institute at the National Institutes of Health ( R01 CA136783 to C.S.M., R01 CA134722 and K05 CA160724 to K.C.O., U24 CA55727 to G.T.A., and the Core Grant P30 CA008748 to Memorial Sloan Kettering Cancer Center). The funding source had no role in the study design, data collection, analysis and interpretation, or in the writing of the manuscript.
- Craniospinal irradiation
- Late effects
- Secondary breast cancer