Breast cancer following spinal irradiation for a childhood cancer: A report from the Childhood Cancer Survivor Study

Chaya S. Moskowitz, Jyoti Malhotra, Joanne F. Chou, Suzanne L. Wolden, Rita E. Weathers, Marilyn Stovall, Gregory T. Armstrong, Wendy M. Leisenring, Joseph P. Neglia, Leslie L. Robison, Kevin C. Oeffinger

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

It has been suggested that pediatric patients treated with spinal irradiation may have an elevated risk of breast cancer. Among a cohort of 363 long-term survivors of a pediatric central nervous system tumor or leukemia treated with spinal irradiation, there was little evidence of an increased breast cancer risk.

Original languageEnglish (US)
Pages (from-to)213-216
Number of pages4
JournalRadiotherapy and Oncology
Volume117
Issue number2
DOIs
StatePublished - Nov 1 2015

Bibliographical note

Funding Information:
This work was supported by the National Cancer Institute at the National Institutes of Health ( R01 CA136783 to C.S.M., R01 CA134722 and K05 CA160724 to K.C.O., U24 CA55727 to G.T.A., and the Core Grant P30 CA008748 to Memorial Sloan Kettering Cancer Center). The funding source had no role in the study design, data collection, analysis and interpretation, or in the writing of the manuscript.

Keywords

  • Craniospinal irradiation
  • Late effects
  • Secondary breast cancer

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