Brain imaging with improved acceleration and SNR at 7 Tesla obtained with 64-channel receive array

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Abstract

Purpose: Despite the clear synergy between high channel counts in a receive array and magnetic fields ≥ 7 Tesla, to date such systems have been restricted to a maximum of 32 channels. Here, we examine SNR gains at 7 Tesla in unaccelerated and accelerated images with a 64-receive channel (64Rx) RF coil. Methods: A 64Rx coil was built using circular loops tiled in 2 separable sections of a close-fitting form; custom designed preamplifier boards were integrated into each coil element. A 16-channel transmitter arranged in 2 rows along the z-axis was employed. The performance of the 64Rx array was experimentally compared to that of an industry-standard 32-channel receive (32Rx) array for SNR in unaccelerated images and for noise amplification under parallel imaging. Results: SNR gains were observed in the periphery but not in the center of the brain in unaccelerated imaging compared to the 32Rx coil. With either 1D or 2D undersampling of k-space, or with slice acceleration together with 1D undersampling of k-space, significant reductions in g-factor noise were observed throughout the brain, yielding effective gains in SNR in the entire brain compared to the 32Rx coil. Task-based FMRI data with 12-fold 2D (slice and phase-encode) acceleration yielded excellent quality functional maps with the 64Rx coil but was significantly beyond the capabilities of the 32Rx coil. Conclusion: The results confirm the expectations from modeling studies and demonstrate that whole-brain studies with up to 16-fold, 2D acceleration would be feasible with the 64Rx coil.

Original languageEnglish (US)
Pages (from-to)495-509
Number of pages15
JournalMagnetic resonance in medicine
Volume82
Issue number1
DOIs
StatePublished - Jul 1 2019

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Neuroimaging
Brain
Noise
Magnetic Fields
Industry

Keywords

  • RF coils
  • functional imaging
  • multiband
  • neuroimaging
  • parallel imaging
  • simultaneous multislice

PubMed: MeSH publication types

  • Journal Article

Cite this

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title = "Brain imaging with improved acceleration and SNR at 7 Tesla obtained with 64-channel receive array",
abstract = "Purpose: Despite the clear synergy between high channel counts in a receive array and magnetic fields ≥ 7 Tesla, to date such systems have been restricted to a maximum of 32 channels. Here, we examine SNR gains at 7 Tesla in unaccelerated and accelerated images with a 64-receive channel (64Rx) RF coil. Methods: A 64Rx coil was built using circular loops tiled in 2 separable sections of a close-fitting form; custom designed preamplifier boards were integrated into each coil element. A 16-channel transmitter arranged in 2 rows along the z-axis was employed. The performance of the 64Rx array was experimentally compared to that of an industry-standard 32-channel receive (32Rx) array for SNR in unaccelerated images and for noise amplification under parallel imaging. Results: SNR gains were observed in the periphery but not in the center of the brain in unaccelerated imaging compared to the 32Rx coil. With either 1D or 2D undersampling of k-space, or with slice acceleration together with 1D undersampling of k-space, significant reductions in g-factor noise were observed throughout the brain, yielding effective gains in SNR in the entire brain compared to the 32Rx coil. Task-based FMRI data with 12-fold 2D (slice and phase-encode) acceleration yielded excellent quality functional maps with the 64Rx coil but was significantly beyond the capabilities of the 32Rx coil. Conclusion: The results confirm the expectations from modeling studies and demonstrate that whole-brain studies with up to 16-fold, 2D acceleration would be feasible with the 64Rx coil.",
keywords = "RF coils, functional imaging, multiband, neuroimaging, parallel imaging, simultaneous multislice",
author = "Kamil Ugurbil and Auerbach, {Edward J} and Steen Moeller and Grant, {Andrea N} and Xiaoping Wu and {Van de Moortele}, Pierre-Francois and Olman, {Cheryl A} and Lance DelaBarre and Scott Schillak and Radder, {Jerahmie W} and Lagore, {Russell L} and Gregor Adriany",
year = "2019",
month = "7",
day = "1",
doi = "10.1002/mrm.27695",
language = "English (US)",
volume = "82",
pages = "495--509",
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TY - JOUR

T1 - Brain imaging with improved acceleration and SNR at 7 Tesla obtained with 64-channel receive array

AU - Ugurbil, Kamil

AU - Auerbach, Edward J

AU - Moeller, Steen

AU - Grant, Andrea N

AU - Wu, Xiaoping

AU - Van de Moortele, Pierre-Francois

AU - Olman, Cheryl A

AU - DelaBarre, Lance

AU - Schillak, Scott

AU - Radder, Jerahmie W

AU - Lagore, Russell L

AU - Adriany, Gregor

PY - 2019/7/1

Y1 - 2019/7/1

N2 - Purpose: Despite the clear synergy between high channel counts in a receive array and magnetic fields ≥ 7 Tesla, to date such systems have been restricted to a maximum of 32 channels. Here, we examine SNR gains at 7 Tesla in unaccelerated and accelerated images with a 64-receive channel (64Rx) RF coil. Methods: A 64Rx coil was built using circular loops tiled in 2 separable sections of a close-fitting form; custom designed preamplifier boards were integrated into each coil element. A 16-channel transmitter arranged in 2 rows along the z-axis was employed. The performance of the 64Rx array was experimentally compared to that of an industry-standard 32-channel receive (32Rx) array for SNR in unaccelerated images and for noise amplification under parallel imaging. Results: SNR gains were observed in the periphery but not in the center of the brain in unaccelerated imaging compared to the 32Rx coil. With either 1D or 2D undersampling of k-space, or with slice acceleration together with 1D undersampling of k-space, significant reductions in g-factor noise were observed throughout the brain, yielding effective gains in SNR in the entire brain compared to the 32Rx coil. Task-based FMRI data with 12-fold 2D (slice and phase-encode) acceleration yielded excellent quality functional maps with the 64Rx coil but was significantly beyond the capabilities of the 32Rx coil. Conclusion: The results confirm the expectations from modeling studies and demonstrate that whole-brain studies with up to 16-fold, 2D acceleration would be feasible with the 64Rx coil.

AB - Purpose: Despite the clear synergy between high channel counts in a receive array and magnetic fields ≥ 7 Tesla, to date such systems have been restricted to a maximum of 32 channels. Here, we examine SNR gains at 7 Tesla in unaccelerated and accelerated images with a 64-receive channel (64Rx) RF coil. Methods: A 64Rx coil was built using circular loops tiled in 2 separable sections of a close-fitting form; custom designed preamplifier boards were integrated into each coil element. A 16-channel transmitter arranged in 2 rows along the z-axis was employed. The performance of the 64Rx array was experimentally compared to that of an industry-standard 32-channel receive (32Rx) array for SNR in unaccelerated images and for noise amplification under parallel imaging. Results: SNR gains were observed in the periphery but not in the center of the brain in unaccelerated imaging compared to the 32Rx coil. With either 1D or 2D undersampling of k-space, or with slice acceleration together with 1D undersampling of k-space, significant reductions in g-factor noise were observed throughout the brain, yielding effective gains in SNR in the entire brain compared to the 32Rx coil. Task-based FMRI data with 12-fold 2D (slice and phase-encode) acceleration yielded excellent quality functional maps with the 64Rx coil but was significantly beyond the capabilities of the 32Rx coil. Conclusion: The results confirm the expectations from modeling studies and demonstrate that whole-brain studies with up to 16-fold, 2D acceleration would be feasible with the 64Rx coil.

KW - RF coils

KW - functional imaging

KW - multiband

KW - neuroimaging

KW - parallel imaging

KW - simultaneous multislice

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U2 - 10.1002/mrm.27695

DO - 10.1002/mrm.27695

M3 - Article

VL - 82

SP - 495

EP - 509

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

SN - 0740-3194

IS - 1

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