Brain areas associated with bulbocapnine catalepsy

L. F. Tseng, E. Wei, H. H. Loh

Research output: Contribution to journalArticlepeer-review

Abstract

Intracerebral micro-injections of bulbocapnine were made to locate the brain sites of action for the production of catelepsy in rats. The catalepsy was induced after bilateral injection of bulbocapnine into striatal areas. The thalamus and the areas in mesencephalon are less sensitive to bulbocapnine for the production of catalepsy. The results support the suggestion that the bulbocapnine-induced catalepsy arose from the blockade of dopaminergic receptors in corpus striatum.

Original languageEnglish (US)
Pages (from-to)363-366
Number of pages4
JournalEuropean Journal of Pharmacology
Volume22
Issue number3
DOIs
StatePublished - Jun 1973

Bibliographical note

Funding Information:
This study was supported in part by USPHS Grant DA-00564 and MH-19944. Dr. H.H. Loh is a recipient of NIMH Research Scientist Development Award K2-MH-70554. The authors wish to thank Barbara Halperin for assistance in preparation of this manuscript.

Keywords

  • Bulbocapnine
  • Catalepsy
  • Corpus striatum

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