Bone Strength Is Preserved Following Bariatric Surgery

Lesley M. Scibora, Henry Buchwald, Moira A. Petit, Julie Hughes, Sayeed Ikramuddin

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: There is an increasing concern that bariatric surgery results in excessive bone loss as demonstrated by studies that use areal bone mineral density (aBMD) outcomes by dual energy X-ray absorptiometry (DXA). Thus, we explored the effect of bariatric surgery on bone mechanical strength.Methods: Bone strength and body composition outcomes were measured in 21 adults (age 45.3 years; BMI 45.7 kg/m2) at baseline (pre-surgery) and 3, 6, and 12 months post-surgery. Bone geometry, density and strength were assessed by peripheral quantitative computed tomography (pQCT) at the distal (4 %) sites of the radius and tibia and at the midshaft sites of the tibia (66 %) and radius (50 %). Participants were divided into tertiles (high, medium, and low) of percentage weight loss at 6 months post-surgery.Results: Participants in all three tertiles lost significant body weight by 6 months post-surgery (mean loss −5 to −30 %, all p < 0.05). At 6 months, all tertiles lost significant fat mass (−9 to −51 %, all p < 0.05), but only the high tertile lost significant fat-free mass (−8 %, p < 0.05). Despite a slight increase in tibia bone strength (SSIp) at 3 months (+1.1 %, p < 0.05), estimates of bone strength at the radius and tibia sites did not change at later post-surgical time points regardless of weight loss.Conclusions: Contrary to DXA-based aBMD outcomes in the current literature, these results suggest that bone strength was preserved up to 12 months following bariatric surgery. Future longer-term studies exploring bone strength and geometry are needed to confirm these findings.

Original languageEnglish (US)
Pages (from-to)263-270
Number of pages8
JournalObesity Surgery
Volume25
Issue number2
DOIs
StatePublished - Jan 1 2015

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Bariatric Surgery
Bone and Bones
Tibia
Bone Density
Photon Absorptiometry
Weight Loss
Fats
Operative Time
Body Composition
Tomography
Body Weight

Keywords

  • Bariatric surgery
  • Bone
  • Bone mineral density
  • Bone strength
  • Morbid obesity
  • Peripheral quantitative computed tomography (pQCT)

Cite this

Bone Strength Is Preserved Following Bariatric Surgery. / Scibora, Lesley M.; Buchwald, Henry; Petit, Moira A.; Hughes, Julie; Ikramuddin, Sayeed.

In: Obesity Surgery, Vol. 25, No. 2, 01.01.2015, p. 263-270.

Research output: Contribution to journalArticle

Scibora, Lesley M. ; Buchwald, Henry ; Petit, Moira A. ; Hughes, Julie ; Ikramuddin, Sayeed. / Bone Strength Is Preserved Following Bariatric Surgery. In: Obesity Surgery. 2015 ; Vol. 25, No. 2. pp. 263-270.
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abstract = "Background: There is an increasing concern that bariatric surgery results in excessive bone loss as demonstrated by studies that use areal bone mineral density (aBMD) outcomes by dual energy X-ray absorptiometry (DXA). Thus, we explored the effect of bariatric surgery on bone mechanical strength.Methods: Bone strength and body composition outcomes were measured in 21 adults (age 45.3 years; BMI 45.7 kg/m2) at baseline (pre-surgery) and 3, 6, and 12 months post-surgery. Bone geometry, density and strength were assessed by peripheral quantitative computed tomography (pQCT) at the distal (4 {\%}) sites of the radius and tibia and at the midshaft sites of the tibia (66 {\%}) and radius (50 {\%}). Participants were divided into tertiles (high, medium, and low) of percentage weight loss at 6 months post-surgery.Results: Participants in all three tertiles lost significant body weight by 6 months post-surgery (mean loss −5 to −30 {\%}, all p < 0.05). At 6 months, all tertiles lost significant fat mass (−9 to −51 {\%}, all p < 0.05), but only the high tertile lost significant fat-free mass (−8 {\%}, p < 0.05). Despite a slight increase in tibia bone strength (SSIp) at 3 months (+1.1 {\%}, p < 0.05), estimates of bone strength at the radius and tibia sites did not change at later post-surgical time points regardless of weight loss.Conclusions: Contrary to DXA-based aBMD outcomes in the current literature, these results suggest that bone strength was preserved up to 12 months following bariatric surgery. Future longer-term studies exploring bone strength and geometry are needed to confirm these findings.",
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KW - Morbid obesity

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