Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients

Bei Jia; Liru Wang; David F. Claxton; W. Christopher Ehmann; Witold B. Rybka; Shin Mineishi; Syed Rizvi; Hiroko Shike; Michael Bayerl; Todd D. Schell; Raymond J. Hohl; Hong Zheng

doi:10.1038/s41408-018-0069-4

Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients

Bei Jia, Liru Wang, David F. Claxton, W. Christopher Ehmann, Witold B. Rybka, Shin Mineishi, Syed Rizvi, Hiroko Shike, Michael Bayerl, Todd D. Schell, Raymond J. Hohl, Hong Zheng

Research output: Contribution to journal › Letter › peer-review

48 Scopus citations

Original language	English (US)
Article number	34
Journal	Blood cancer journal
Volume	8
Issue number	3
DOIs	https://doi.org/10.1038/s41408-018-0069-4
State	Published - Mar 1 2018
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by the American Society of Hematologist (ASH) Scholar Award, American Cancer Society Institutional Research Grant ACS IRG 124171-IRG-13-043-02 and the Kiesendahl Endowment funding. We thank all our patients for their trust, understanding, and willingness to provide their blood samples for our research.

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Jia, B., Wang, L., Claxton, D. F., Ehmann, W. C., Rybka, W. B., Mineishi, S., Rizvi, S., Shike, H., Bayerl, M., Schell, T. D., Hohl, R. J., & Zheng, H. (2018). Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients. Blood cancer journal, 8(3), Article 34. https://doi.org/10.1038/s41408-018-0069-4

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title = "Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients",

author = "Bei Jia and Liru Wang and Claxton, {David F.} and Ehmann, {W. Christopher} and Rybka, {Witold B.} and Shin Mineishi and Syed Rizvi and Hiroko Shike and Michael Bayerl and Schell, {Todd D.} and Hohl, {Raymond J.} and Hong Zheng",

note = "Funding Information: This work was supported by the American Society of Hematologist (ASH) Scholar Award, American Cancer Society Institutional Research Grant ACS IRG 124171-IRG-13-043-02 and the Kiesendahl Endowment funding. We thank all our patients for their trust, understanding, and willingness to provide their blood samples for our research.",

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T1 - Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients

AU - Jia, Bei

AU - Wang, Liru

AU - Claxton, David F.

AU - Ehmann, W. Christopher

AU - Rybka, Witold B.

AU - Mineishi, Shin

AU - Rizvi, Syed

AU - Shike, Hiroko

AU - Bayerl, Michael

AU - Schell, Todd D.

AU - Hohl, Raymond J.

AU - Zheng, Hong

N1 - Funding Information: This work was supported by the American Society of Hematologist (ASH) Scholar Award, American Cancer Society Institutional Research Grant ACS IRG 124171-IRG-13-043-02 and the Kiesendahl Endowment funding. We thank all our patients for their trust, understanding, and willingness to provide their blood samples for our research.

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ER -

Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients

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