Body surface laplacian mapping of anterior myocardial infarction in man

H. Tsai, H. Ceccoli, B. Avitall, B. He

Research output: Contribution to journalArticlepeer-review


The recent development of body surface Laplacian mapping has shown increased capability for resolving multiple epimyocardial electrical events. For the myocardial infarction (MI) patient, accurate localization of the site and extent of infarct remains a critical issue, and the body surface Laplacian map (BSLM) may serve as a useful tool for this purpose. One hundred and ® fty lead electrocardiogram (ECG) recordings were taken over the anterolateral chest of ® ve anterior MI patients. After 20-beat averaging of the potential ECGs, the Laplacian ECGs were calculated using a ® nite di. erence estimation algorithm. BSLMs of the anterior MI patients showed a highly localized early negativity overlying the site of infarct, which was determined by echocardiography. Compared to the corresponding body surface potential maps, the BSLMs showed a more localized area of activity corresponding to the anterior infarct site, as judged by echocardiographic interpretation.

Original languageEnglish (US)
Pages (from-to)607-619
Number of pages13
Issue number7-8
StatePublished - 2001

Bibliographical note

Funding Information:
Received 20 Decembe, 2r0;0acc0eptde28 Apr, 2i0l.01 We would like to thank Dr. Dongsheng Wu for valuable discussions and DonggnWu,in Sriram Srinivasan, Vanee Virasch, and Siya Nedumgotl tforiassistance in data collection and experimental peparratio. Thins work was supported in part by grants from the Whitaker Foundatio, thenNihn Kohoden R&D Cter,etenhBn rFunacnitsLiboraary, atdonthe University of Illinos atiChicago Campus Research Board. Addrsecorrsespondence to Bin He, Universy ioftIllinois at Chicago, MC-063, SEO 218, 851 S. Morgan St. Chicag, IoL 660, 0USA7. E-mail:


  • Body surface Laplacian mapping
  • Body surface potential mapping
  • Laplacian ECG
  • Myocardial infarction


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