Body mass index and uterine receptivity in the oocyte donation model

Objective: To evaluate the relationship of body mass index (BMI) to uterine receptivity under conditions of programmed hormonal support and standardized embryo quality. Design: Retrospective cohort study. Setting: A tertiary referral center. Patient(s): Ninety-seven consecutive first-cycle recipients of anonymous oocyte donation. Intervention(s): After programmed hormone replacement, recipients had transfer of embryos derived from oocyte donation. Anonymous oocyte donors received ovarian stimulation and underwent transvaginal ultrasound-guided oocyte retrieval. Main outcome measure(s): A receiver operator characteristic (ROC) curve of implantation versus BMI. Result(s): Area under the ROC curve was 0.51, 95% confidence interval (CI) 0.41-0.62, suggesting no relationship between BMI and implantation. There was no difference in implantation rates between obese (BMI ≥30) and nonobese (BMI <30) recipients, odds ratio 1.1, 95% CI 0.5-2.4. Conclusion(s): Uterine receptivity was unimpaired in women with increased BMI when hormonal support and embryo quality were standardized.