Body builder: from synthetic cells to engineered tissues

Shiqi Hu, Brenda M Ogle, Ke Cheng

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

It is estimated that 18 Americans die every day waiting for an organ donation. And even if a patient receives the organ that s/he needs, there is still >10% chance that the new organ will not work. The field of tissue engineering and regenerative medicine aims to actively use a patient's own cells, plus biomaterials and factors, to grow specific tissues for replacement or to restore normal functions of that organ, which would eliminate the need for donors and the risk of alloimmune rejection. In this review, we summarized recent advances in fabricating synthetic cells, with a specific focus on their application to cardiac regenerative medicine and tissue engineering. At the end, we pointed to challenges and future directions for the field.

Original languageEnglish (US)
Pages (from-to)37-42
Number of pages6
JournalCurrent Opinion in Cell Biology
Volume54
DOIs
StatePublished - Oct 1 2018

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Artificial Cells
Regenerative Medicine
Tissue Engineering
Tissue and Organ Procurement
Biocompatible Materials
Tissue Donors
Direction compound

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural
  • Review

Cite this

Body builder : from synthetic cells to engineered tissues. / Hu, Shiqi; Ogle, Brenda M; Cheng, Ke.

In: Current Opinion in Cell Biology, Vol. 54, 01.10.2018, p. 37-42.

Research output: Contribution to journalReview article

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