BMI and diabetes risk in Singaporean Chinese

Andrew O. Odegaard, Woon Puay Koh, Gabrielle Vazquez, Kazuko Arakawa, Hin Peng Lee, Mimi C. Yu, Mark A. Pereira

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

OBJECTIVE - Increased BMI is a robust risk factor for type 2 diabetes. Paradoxically, South Asians have relatively low BMIs despite their high prevalence of type 2 diabetes. We examined the association between BMI and incident type 2 diabetes because detailed prospective cohort data on this topic in Asians are scarce. RESEARCH DESIGN AND METHODS - This study was a prospective analysis of 37,091 men and women aged 45-74 years in the Singapore Chinese Health Study, using Cox regression analysis. RESULTS - Risk of incident type 2 diabetes significantly increased beginning with BMIs 18.5-23.0 kg/m2 (relative risk 2.47 [95% CI 1.75-3.48]) and continued in a monotonic fashion across the spectrum of BMI. Results were stronger for younger than for older adults. CONCLUSIONS - BMIs considered lean and normal in Singaporean Chinese are strongly associated with increased risk of incident type 2 diabetes. This association weakened with advanced age but remained significant.

Original languageEnglish (US)
Pages (from-to)1104-1106
Number of pages3
JournalDiabetes care
Volume32
Issue number6
DOIs
StatePublished - Jun 1 2009

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    Odegaard, A. O., Koh, W. P., Vazquez, G., Arakawa, K., Lee, H. P., Yu, M. C., & Pereira, M. A. (2009). BMI and diabetes risk in Singaporean Chinese. Diabetes care, 32(6), 1104-1106. https://doi.org/10.2337/dc08-1674