TY - JOUR
T1 - Blood supply and safety in the developing world
T2 - Considerations for emerging markets
AU - Riley, William
AU - McCullough, Jeffry
PY - 2012/10
Y1 - 2012/10
N2 - Assuring a safe and adequate blood supply in developing nations such as emerging markets is a daunting challenge that directly affects fundamental health metrics of a country. Numerous mortalities can be reduced when an effective national blood transfusion system is in place. These mortalities include leading causes of death such as maternal hemorrhage, sickle cell anemia, and malaria. There exists a circular relationship between blood supply and safety: efforts to ensure donor and recipient safety reduce the population of eligible voluntary blood donors, which in turn restricts blood supply. In this article we describe the main issues for blood supply in developing nations and emerging markets, identify the major causes and impact of transfusion transmitted infections, present a safety model that describes the relationship between defensive barriers in depth to assure safe blood, its effectiveness, and the impact it has on safe blood supply. The results of this study apply to the forty seven nations sub-Saharan Africa (SSA) based on an extrapolation from a focused analysis on twenty two African countries. Finally, we discuss strategies for blood safety and supply in developing nations.
AB - Assuring a safe and adequate blood supply in developing nations such as emerging markets is a daunting challenge that directly affects fundamental health metrics of a country. Numerous mortalities can be reduced when an effective national blood transfusion system is in place. These mortalities include leading causes of death such as maternal hemorrhage, sickle cell anemia, and malaria. There exists a circular relationship between blood supply and safety: efforts to ensure donor and recipient safety reduce the population of eligible voluntary blood donors, which in turn restricts blood supply. In this article we describe the main issues for blood supply in developing nations and emerging markets, identify the major causes and impact of transfusion transmitted infections, present a safety model that describes the relationship between defensive barriers in depth to assure safe blood, its effectiveness, and the impact it has on safe blood supply. The results of this study apply to the forty seven nations sub-Saharan Africa (SSA) based on an extrapolation from a focused analysis on twenty two African countries. Finally, we discuss strategies for blood safety and supply in developing nations.
KW - Blood supply
KW - Developing countries
KW - Emerging markets
KW - Patient safety
UR - http://www.scopus.com/inward/record.url?scp=84867602073&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867602073&partnerID=8YFLogxK
U2 - 10.5912/jcb565
DO - 10.5912/jcb565
M3 - Article
AN - SCOPUS:84867602073
SN - 1462-8732
VL - 18
SP - 50
EP - 57
JO - Journal of Commercial Biotechnology
JF - Journal of Commercial Biotechnology
IS - 4
ER -