Blood pressure and arterial compliance in young adults: The Minnesota Children's Blood Pressure Study

Donna K. Arnett, Stephen P. Glasser, Gary McVeigh, Ronald Prineas, Stanley Finklestein, Richard Donahue, Jay N. Cohn, Alan Sinaiko

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

The aim of this study was to assess the relation between blood pressure (BP) and arterial compliance in a healthy sample of young adults. School children (aged 10 to 14 years at entry) were surveyed in 1977 to 1978, and 1207 were followed once to twice yearly until age 23 years. Arterial compliance was measured in 179 adults at the last follow-up visit. The sample included individuals in the upper tertile of systolic BP during the last three follow-up visits and race- and sex-matched individuals in the lower two tertiles. We obtained radial artery waveforms using a calibrated tonometer device and characterized waveform morphology to determine large artery (C1) and oscillatory (C2) compliance. Blood pressure was measured using random zero sphygmomanometers. The mean and standard deviation of C1 was 2.13 ± 0.59 mL/mm Hg and of C2 was 0.083 ± 0.02 mL/mm Hg. Systolic BP was inversely related to C1 (P < .001) and C2 (P < .01) after adjustment for gender, height, weight, insulin, and HDL and LDL cholesterol. After adjustment, a 1 SD change in systolic BP was associated with a -0.30 mL/mm Hg change in C1 and a -.008 mL/mm Hg change in C2. Data from the Minnesota Children's Blood Pressure Study indicate that systolic BP is inversely related to arterial compliance, particularly C1 (the large artery, or capacitive compliance).

Original languageEnglish (US)
Pages (from-to)200-205
Number of pages6
JournalAmerican Journal of Hypertension
Volume14
Issue number3
DOIs
StatePublished - Mar 20 2001

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Compliance
Young Adult
Arterial Pressure
Blood Pressure
Arteries
Sphygmomanometers
Radial Artery
LDL Cholesterol
HDL Cholesterol
Insulin
Weights and Measures
Equipment and Supplies

Keywords

  • Arterial compliance
  • Blood pressure
  • Pediatrics

Cite this

Blood pressure and arterial compliance in young adults : The Minnesota Children's Blood Pressure Study. / Arnett, Donna K.; Glasser, Stephen P.; McVeigh, Gary; Prineas, Ronald; Finklestein, Stanley; Donahue, Richard; Cohn, Jay N.; Sinaiko, Alan.

In: American Journal of Hypertension, Vol. 14, No. 3, 20.03.2001, p. 200-205.

Research output: Contribution to journalArticle

Arnett, Donna K. ; Glasser, Stephen P. ; McVeigh, Gary ; Prineas, Ronald ; Finklestein, Stanley ; Donahue, Richard ; Cohn, Jay N. ; Sinaiko, Alan. / Blood pressure and arterial compliance in young adults : The Minnesota Children's Blood Pressure Study. In: American Journal of Hypertension. 2001 ; Vol. 14, No. 3. pp. 200-205.
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