Blood lipids in young men followed 32 years

Richard F. Gillum; Henry L. Taylor; Josef Brožek; Joseph Anderson; Henry Blackburn

doi:10.1016/0021-9681(82)90015-7

Blood lipids in young men followed 32 years

Richard F. Gillum
, Henry L. Taylor
, Josef Brožek
, Joseph Anderson
, Henry Blackburn

Epidemiology & Community Health

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The relationship of baseline characteristics to serum cholesterol at baseline (CHL47) when aged 16-25 (mean 20.5) yr and at 32-yr follow-up (CHL79) was assessed in 162 men. Mean CHL rose over the follow-up period. CHL47 predicted CHL79 (r = 0.61, p < 0.001) but not CHL79-CHL47. The mean (± SD) weight change (DW) was 12.0 kg (± 26.0 kg). DW was not significantly related to CHL47, but was independently related to CHL79-CHL47 (r = 0.30, p < 0.001). Age, height, DW, any of 7 measures of baseline obesity and CHL47 predicted CHL79 with R² of 0.40 and CHL79-CHL47 with R² of 0.37. Thus, weight change but not baseline relative weight was a determinant of serum cholesterol change from youth to middle age. There was strong tracking of serum cholesterol over this period.

Original language	English (US)
Pages (from-to)	635-641
Number of pages	7
Journal	Journal of Chronic Diseases
Volume	35
Issue number	8
DOIs	https://doi.org/10.1016/0021-9681(82)90015-7
State	Published - 1982

Bibliographical note

Funding Information:
*This work was supported by NIH National Heart, Lung and Blood Institute Grant No. HL23482, Minnesota Medical Foundation and by Research Career Development Award 1 K04 HLO0329.

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title = "Blood lipids in young men followed 32 years",

abstract = "The relationship of baseline characteristics to serum cholesterol at baseline (CHL47) when aged 16-25 (mean 20.5) yr and at 32-yr follow-up (CHL79) was assessed in 162 men. Mean CHL rose over the follow-up period. CHL47 predicted CHL79 (r = 0.61, p < 0.001) but not CHL79-CHL47. The mean (± SD) weight change (DW) was 12.0 kg (± 26.0 kg). DW was not significantly related to CHL47, but was independently related to CHL79-CHL47 (r = 0.30, p < 0.001). Age, height, DW, any of 7 measures of baseline obesity and CHL47 predicted CHL79 with R2 of 0.40 and CHL79-CHL47 with R2 of 0.37. Thus, weight change but not baseline relative weight was a determinant of serum cholesterol change from youth to middle age. There was strong tracking of serum cholesterol over this period.",

author = "Gillum, \{Richard F.\} and Taylor, \{Henry L.\} and Josef Bro{\v z}ek and Joseph Anderson and Henry Blackburn",

note = "Funding Information: *This work was supported by NIH National Heart, Lung and Blood Institute Grant No. HL23482, Minnesota Medical Foundation and by Research Career Development Award 1 K04 HLO0329.",

year = "1982",

doi = "10.1016/0021-9681(82)90015-7",

language = "English (US)",

volume = "35",

pages = "635--641",

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T1 - Blood lipids in young men followed 32 years

AU - Gillum, Richard F.

AU - Taylor, Henry L.

AU - Brožek, Josef

AU - Anderson, Joseph

AU - Blackburn, Henry

N1 - Funding Information: *This work was supported by NIH National Heart, Lung and Blood Institute Grant No. HL23482, Minnesota Medical Foundation and by Research Career Development Award 1 K04 HLO0329.

PY - 1982

Y1 - 1982

N2 - The relationship of baseline characteristics to serum cholesterol at baseline (CHL47) when aged 16-25 (mean 20.5) yr and at 32-yr follow-up (CHL79) was assessed in 162 men. Mean CHL rose over the follow-up period. CHL47 predicted CHL79 (r = 0.61, p < 0.001) but not CHL79-CHL47. The mean (± SD) weight change (DW) was 12.0 kg (± 26.0 kg). DW was not significantly related to CHL47, but was independently related to CHL79-CHL47 (r = 0.30, p < 0.001). Age, height, DW, any of 7 measures of baseline obesity and CHL47 predicted CHL79 with R2 of 0.40 and CHL79-CHL47 with R2 of 0.37. Thus, weight change but not baseline relative weight was a determinant of serum cholesterol change from youth to middle age. There was strong tracking of serum cholesterol over this period.

AB - The relationship of baseline characteristics to serum cholesterol at baseline (CHL47) when aged 16-25 (mean 20.5) yr and at 32-yr follow-up (CHL79) was assessed in 162 men. Mean CHL rose over the follow-up period. CHL47 predicted CHL79 (r = 0.61, p < 0.001) but not CHL79-CHL47. The mean (± SD) weight change (DW) was 12.0 kg (± 26.0 kg). DW was not significantly related to CHL47, but was independently related to CHL79-CHL47 (r = 0.30, p < 0.001). Age, height, DW, any of 7 measures of baseline obesity and CHL47 predicted CHL79 with R2 of 0.40 and CHL79-CHL47 with R2 of 0.37. Thus, weight change but not baseline relative weight was a determinant of serum cholesterol change from youth to middle age. There was strong tracking of serum cholesterol over this period.

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U2 - 10.1016/0021-9681(82)90015-7

DO - 10.1016/0021-9681(82)90015-7

M3 - Article

C2 - 7096527

AN - SCOPUS:0020068133

SN - 0021-9681

VL - 35

SP - 635

EP - 641

JO - Journal of Chronic Diseases

JF - Journal of Chronic Diseases

IS - 8

ER -

Blood lipids in young men followed 32 years

Abstract

Bibliographical note

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