Blockade of OX40 Signals Enhance Survival of Xenoislet Grafts in Spontaneously Diabetic NOD Mice

Keyphrases

• OX40 100%
• Signal Enhancement 100%
• Non-obese Diabetic Mice 100%
• Cytotoxic T-lymphocyte antigen-4 (CTLA-4) 66%
• T Cells 33%
• Diabetic 25%
• Diabetogenic 25%
• Treg 16%
• Effector Function 16%
• Adoptive Transfer 16%
• Blood Glucose Measurement 16%
• Graft Survival 16%
• Novel Therapeutic Targets 8%
• Diabetes 8%
• Lymph Node 8%
• SCID Mice 8%
• NOD Mice 8%
• Autoimmune 8%
• Islet Xenograft 8%
• CD28 8%
• Porcine Islets 8%
• Type 1 Diabetic Patient 8%
• Diabetes Incidence 8%
• Spleen 8%
• Diabetic Animals 8%
• Transfer Research 8%
• Xenograft Model 8%
• Kidney Capsule 8%
• Graft Protection 8%
• Delayed Rejection 8%
• Mechanistic Studies 8%
• Costimulatory Molecules 8%
• Preactivated 8%

Medicine and Dentistry

• NOD Mice 100%
• OX40 Ligand 100%
• Abatacept 100%
• T Cell 50%
• Diabetes 25%
• Diabetes Mellitus 25%
• Graft Survival 25%
• Blood Glucose 25%
• Xenograft 12%
• Lymph Node 12%
• Kidney Capsule 12%
• Adoptive Transfer 12%
• Adoptive Transfer Study 12%
• Immunoglobulin Antibody 12%

Immunology and Microbiology

• OX40L 100%
• Nonobese Diabetic Mouse 100%
• Abatacept 100%
• T Cell 50%
• Regulatory T Cell 25%
• Glucose Blood Level 25%
• Xenograft 12%
• Adoptive Transfer Study 12%
• CD28 12%
• Kidney Capsule 12%
• Immunoglobulin Antibody 12%
• Lymph Node 12%