Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

Andrea L. Harzstark; Charles J. Ryan; Eric J. Small

doi:10.2217/1745509X.2.6.943

Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

Andrea L. Harzstark, Charles J. Ryan, Eric J. Small

Research output: Contribution to journal › Review article › peer-review

Abstract

Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.

Original language	English (US)
Pages (from-to)	943-954
Number of pages	12
Journal	Aging Health
Volume	2
Issue number	6
DOIs	https://doi.org/10.2217/1745509X.2.6.943
State	Published - Dec 2006
Externally published	Yes

Keywords

Bisphosphonates
Bone metastasis
Prostate cancer
Skeletal complications of malignancy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2217/1745509X.2.6.943

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title = "Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer",

abstract = "Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.",

keywords = "Bisphosphonates, Bone metastasis, Prostate cancer, Skeletal complications of malignancy",

author = "Harzstark, {Andrea L.} and Ryan, {Charles J.} and Small, {Eric J.}",

year = "2006",

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language = "English (US)",

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TY - JOUR

T1 - Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

AU - Harzstark, Andrea L.

AU - Ryan, Charles J.

AU - Small, Eric J.

PY - 2006/12

Y1 - 2006/12

N2 - Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.

AB - Osseous metastases and osteoporotic fractures are a serious problem in patients with prostate cancer. As androgen-deprivation therapy is being used earlier in the course of the disease, the risk of osteoporosis and insufficiency fractures is increasing. In this review, the contribution of androgen-deprivation therapy to osteoporosis and bone metastases will be discussed. The role of bisphosphonates in treating osteoporosis and bone metastases will also be reviewed. The review will conclude with a discussion of the toxicities associated with bisphosphonate use.

KW - Bisphosphonates

KW - Bone metastasis

KW - Prostate cancer

KW - Skeletal complications of malignancy

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DO - 10.2217/1745509X.2.6.943

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SN - 1745-509X

VL - 2

SP - 943

EP - 954

JO - Aging Health

JF - Aging Health

IS - 6

ER -

Bisphosphonate therapy for the treatment of skeletal complications in patients with prostate cancer

Abstract

Keywords

UN SDGs

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