Bipolar Androgen Therapy: A Paradoxical Approach for the Treatment of Castration-resistant Prostate Cancer

Michael T. Schweizer, Emmanuel S. Antonarakis, Samuel R. Denmeade

Research output: Contribution to journalEditorialpeer-review

18 Scopus citations

Abstract

Bipolar androgen therapy (BAT) is a paradoxical treatment for castrate-resistant prostate cancer whereby testosterone levels are rapidly alternated between supraphysiologic and near-castrate concentrations. Initial studies demonstrated that BAT is safe and produces clinical responses. A trial comparing enzalutamide against BAT is ongoing.

Original languageEnglish (US)
Pages (from-to)323-325
Number of pages3
JournalEuropean Urology
Volume72
Issue number3
DOIs
StatePublished - Sep 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2017 European Association of Urology

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